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PedAM

Pediatric Disease Annotations & Medicines




Disease septicemia
Phenotype C0024312|lymphopenia
Sentences 4
PubMedID- 26529661 Regarding adaptive immunity, sepsis-induced apoptosis leads to lymphopenia in patients with septic shock and it involves all types of t cells (cd4, cd8 and natural killer) except t regulatory cells, thus favoring immunosuppression.
PubMedID- 24489107 Coli exacerbates lymphopenia associated with septicemia and could impair the chances to survive sepsis.
PubMedID- 24387680 Importantly, persistent lymphopenia in sepsis is associated with increased mortality, and lymphocyte depletion (as reflected by lymphopenia) may contribute to morbidity and mortality by impairing host immunity [26,27].
PubMedID- 25793436 Conclusions: hypothermia is associated with higher mortality and an increased risk of persistent lymphopenia in patients with sepsis, and it may be an early clinical predictor of sepsis-induced immunosuppression.

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