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PedAM

Pediatric Disease Annotations & Medicines




Disease septicemia
Phenotype C0011570|depression
Sentences 11
PubMedID- 24887309 We hypothesized that myocardial depression in sepsis is global rather than right-sided; however, our findings suggest that a pac-derived rvef may reflect septic cardiomyopathy better than echocardiography and may have greater diagnostic and prognostic value in mechanically ventilated septic patients.
PubMedID- 23438256 Risk factors include pre-ali depression, durations of stay and sepsis in the icu, and administration of high-dose opiates in the icu.
PubMedID- 23706109 In 1977, using pulmonary artery catheter thermodilution method measured left ventricular stroke work index, observed that not only was left ventricular depression common in patients with sepsis, but was also potentially reversible [2].
PubMedID- 22482045 This review on the mechanisms of cardiac depression in sepsis will include anatomical, histopathological, and pathomechanistic data.
PubMedID- 23691359 Release of cytokines (il1β, il-6, and tnfα), nitric oxide, endotoxins [3], and activation of caspases (caspases 3) [20] in setting of a gram negative bacteremia and sepsis leading to myocardial depression and ventricular dilatation [3] is another theory to explain srte (figure 1).
PubMedID- 22554063 Although left ventricular (lv) depression in sepsis was first reported decades ago [1], it has not been well recognized until the recent widespread use of echocardiography in the intensive care unit (icu) [2].
PubMedID- 23894482 sepsis patients with myocardial depression are at a 50–70% greater risk of mortality than patients without cardiovascular complications [31].
PubMedID- 22761733 Cardiac depression in sepsis is associated with the increased morbidity and mortality.
PubMedID- 26163554 Introduction of mechanical support, including extracorporeal cardiopulmonary resuscitation may be recommendable in cases of severe sepsis with myocardial depression resulting in haemodynamic collapse, however, the option of introduction of an invasive approach needs further examination.
PubMedID- PMC3672759 However, the care of the critically ill patient (that is, myocardial depression in sepsis, heart-lung interactions, and prediction of fluid responsiveness) is not covered in this textbook.
PubMedID- 25973949 Cardiac depression occurs in 40–50% of patients with severe sepsis and raises the mortality rate to 80–90% [10,11].

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