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PedAM

Pediatric Disease Annotations & Medicines




Disease septicemia
Phenotype C0004623|bacterial infections
Sentences 10
PubMedID- 20562695 Study selection: randomized or observational studies of antimicrobial therapy of serious bacterial infections potentially associated with sepsis or septic shock.
PubMedID- 21994624 Toxemia is a poorly defined clinical condition thought to be caused by an excessive inflammatory immune response similar to septicemia associated with systemic bacterial infections.
PubMedID- 21471172 Almog et al reported an odds ratio of 0.07 (0.01 to 0.51) for severe sepsis in patients with bacterial infections (50% of which were pneumonia), although the enormous magnitude of effect detected in this study suggests possible residual confounding.12 frost et al found a hazard ratio of 0.61 (0.41 to 0.92) for mortality due to influenza/pneumonia, although what proportion of these cases were pneumonia is unclear.13 mortensen et al reported an odds ratio of 0.48 (0.36 to 0.64) for mortality 30 days after pneumonia.14 myles et al found a hazard ratio of 0.33 (0.19 to 0.58) for all cause mortality within 30 days of pneumonia.15 of note, this study also used data from thin but included only 12 fatal cases among statin users, compared with 216 in our study.
PubMedID- 24133550 Moreover, in some common viral infections such as influenza, it is known that cases with severe outcome are in most cases due to a superinfection, i.e., the initial viral infection is followed by a bacterial infection, an example being the ‘spanish flu’ in the 1920’s, in which millions of victims did not die from primary infection with influenza h1n1 [4], but from the subsequent bacterial infections, often leading to sepsis [5-7].
PubMedID- 21319346 However, these parameters lack accuracy for early diagnosis of bacteremia.14 pct has recently come to interest as a possible marker of the systemic inflammatory response to infection.7-11 although many studies have established that pct level can be used to identify bacterial infections in patients with sepsis,7,8,11,15 only a few studies have evaluated the capacity of pct findings to rule out bacteremia in outpatients with fever.
PubMedID- 25526004 This condition can lead to severe complications: institutional outbreaks and secondary bacterial infections associated with sepsis and high mortality.
PubMedID- 24011199 As sequelae of systemic bacterial infections, sepsis and septic shock remain the major cause of increased mortality in the intensive care units, accounting for high health care costs every year [1].
PubMedID- 22506087 ‡: bacterial infections include: infections of the urinary tract, sepsis and other infections.
PubMedID- 21927662 Mortality was due to the recurrence of primary liver disease in 21/34 (61.7%), in 13/34 (38.3%) was due to other causes not related to post-olt biliary complications: 5 had fatal cardiovascular diseases, 3 bacterial infections with sepsis, 3 multiorgan failure, 2 de novo malignancies (fig.
PubMedID- 23026673 Experimental animal studies and clinical data have linked the contact system to bacterial infections with implications for sepsis disease.

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