PedAM
Pediatric Disease Annotations & Medicines
| Disease | schistosomiasis |
| Phenotype | C0020538|hypertension |
| Sentences | 14 |
| PubMedID- 22745835 | Two other helminths, schistosoma mansoni and schistosoma japonicum, cause chronic hepatosplenic schistosomiasis, an important cause of pulmonary hypertension and cor pulmonale. |
| PubMedID- 24255616 | A recent study showed that the levels of thrombopoietin and reticulated platelets werenormal in schistosomiasis patients with portal hypertension and that the bone marrowproduces platelets normally(20). |
| PubMedID- 22567478 | Significant morbidity is seen in those patients who develop complications such as end-stage renal diseases, chronic liver diseases with portal hypertension, and cancers associated with schistosomiasis [1–3]. |
| PubMedID- 25746428 | The collateral circulation (porto-caval anastomosis) produced by portal hypertension in cases with hepatosplenic schistosomiasis is essential to divert the schistosome and its ova from the portal to the pulmonary vasculature [7,8]. |
| PubMedID- 26267788 | This study shows that the decrease of flow pressure in portal circulation after splenectomy restores the capacity of hepatocyte synthesis, especially on the factor vii and protein c levels, and these findings suggest that portal hypertension in patients with hepatosplenic schistosomiasis influences liver functioning and the blood coagulation status. |
| PubMedID- 25345171 | Objective: to evaluate the efficacy of splenectomy plus selective pericardial devascularization under endoscope in the treatment of advanced schistosomiasis patients with portal hypertension and hypersplenism so as to explore the minimally invasive and safer surgical treatment. |
| PubMedID- 23875049 | Although bleeding events in hepatosplenic schistosomiasis are associated with portal hypertension [20], the deficient production of coagulation factors does not seem to aggravate the situation due to a balance between the reductions in pro- and anti-coagulation proteins. |
| PubMedID- 21760840 | [22] physiopathologic mechanisms of the development of pulmonary arterial hypertension in patients with schistosomiasis is not clearly known, but probably multifactorial. |
| PubMedID- 21358814 | China, splenectomy, either with or without portosystemic anastomosis, is a general surgical intervention for the treatment of portal hypertension due to hepatosplenic schistosomiasis, which would help to reduce the risk of upper gastrointestinal hemorrhage, cure refractory ascites, recover work capacity, and remove hypersplenism [6]. |
| PubMedID- 25685450 | Examples are colonic sub mucosal and pericolic fibrosis sparing motility, hepatosplenic schistosomiasis without portal hypertension, lower ureteric fibrosis without pelvicalyceal dilatation even when associated with mild to moderate reflux, and bladder fibrosis and calcification without significant urodynamic disturbances. |
| PubMedID- 22348213 | Moreover, brazilian pathologists have found giant follicular lymphomas in 1577 spleens removed from schistosomiasis mansoni patients with severe portal hypertension (andrade et al., 1971; de andrade et al., 1982). |
| PubMedID- 26034376 | We present a case of a patient with hypersplenism secondary to portal hypertension due to hepato-splenic schistosomiasis, which was accompanied by severe and refractory thrombocytopenia. |
| PubMedID- 20332823 | The portal hypertension with hepatosplenic schistosomiasis also plays an important role in the pathogenesis. |
| PubMedID- 20363433 | Objective: the aim of this study was to describe, for the first time, in a pilot study, the endoscopic aspects of the lesions in the small bowel of patients with portal hypertension due to schistosomiasis, using the pillcam sb, and to determine the usefulness of the method for the diagnosis of esophageal varices. |
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