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PedAM

Pediatric Disease Annotations & Medicines




Disease sarcoma
Phenotype C1261473|sarcomas
Sentences 10
PubMedID- 25316466 However, there are still some centers that treat this as sarcoma.4 uterine sarcomas occur primarily in women who are 40-60 years old.5,6 a history of pelvic irradiation was also considered a risk factor in 5-10% of cases.7 compared with the more common types of endometrial cancer, women with uterine sarcoma have a poor prognosis due to the aggressiveness of the disease.5-7 the most frequent prognostic factors include the stage, histological subtype, grade, lymph vascular invasion, and menopausal status.8-10 standard treatment of early stage patients are hysterectomy and surgical staging, and approximately half of these patients develop recurrent disease.10 post-operative radiotherapy reduces local recurrence and improves local disease but does not affect the overall survival.11,12 adjuvant chemotherapy with a single agent, isofosamide or doxorubicin, has been used,11 and combination chemotherapy (which did not show any superiority) has non-proven value over a single agent.13 due to its rarity, heterogeneity, and aggressiveness, there is no consensus regarding the optional therapeutic approaches with considerable variation in the type of surgery and choice of adjuvant treatment.
PubMedID- 25598403 Retroperitoneal sarcomas represent approximately 10–15% of all soft tissue sarcomas, which themselves are rare, accounting for only 1% of all malignancy [3].
PubMedID- 21776304 Liposarcomas represent 10–35% of all soft tissue sarcomas, making them the second most common type after malignant fibrous tumors.
PubMedID- 26413313 Extra skeletal chondrosarcomas represent 2% of all soft tissue sarcomas and are most often found in the thoracic wall (3).
PubMedID- 21165236 Angiosarcomas comprise 1% of all soft tissue sarcomas, with an orbital incidence of 3% of those cases.
PubMedID- 24131748 Synovial sarcomas account for 10 – 15% of all soft tissue sarcomas and usually affect the deep soft tissue of the extremities of young adults [3].
PubMedID- 23661254 The corresponding 5-year relative survival rates were: 83% for localized sarcomas (56% of soft tissue sarcomas were localized when they were diagnosed); 54% for regional stage sarcomas (19% were in this stage); 16% for sarcomas with distant spread (16% were in this stage) (1).
PubMedID- 26293323 Low grade fibromyxoid sarcomas represent approximately 10% of soft tissue sarcomas and are rarely found in the head and neck region.
PubMedID- 23717020 Leiomyosarcomas account for 7% of soft tissue sarcomas, predominantly of visceral location such as the uterus, the gastrointestinal tract or the retroperitoneal space1.
PubMedID- 22208447 Fibrosarcomas account for 15% of all soft tissue sarcomas, which represent only 1% of all malignant tumors of the head and neck region.

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