Home Contact Sitemap

PedAM

Pediatric Disease Annotations & Medicines




Disease sarcoma
Phenotype C0027708|wilms\' tumor
Sentences 2
PubMedID- 23922674 The hallmark of this disease is a ews-wt1 translocation resulting from apposition of the ewing's sarcoma (ews) gene with the wilms' tumor (wt1) gene.
PubMedID- 24624323 This translocation fuses the ewing sarcoma gene (ews) with the wilms' tumor suppressor gene (wt1) to create a gene that likely acts as a transcriptional activator for pro-tumorigenic genes (fang et al., 2008).

Page: 1