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PedAM

Pediatric Disease Annotations & Medicines




Disease sarcoma
Phenotype C0001418|adenocarcinomas
Sentences 2
PubMedID- 25562202 The most common abnormality in adenocarcinomas is mutation of the kirsten rat sarcoma gene (kras), found in 25% of samples.
PubMedID- 25506852 Tumours of the small bowel account for less than 5% of all gastrointestinal malignancies.1 of these, the majority are histologically classed as carcinoid and adenocarcinomas, with sarcomas ranking 5th (∼1.2%).2 leiomyosarcoma is the most common sarcoma, but remains very scarce; with only 26 reported cases of primary small bowel leiomyosarcoma following robust immunohistological techniques.3,4 small bowel tumours are usually asymptomatic at the early stages, and difficult to visualise by upper and lower endoscopy.5 consequently, they often present late with poor prognosis.

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