PedAM
Pediatric Disease Annotations & Medicines
| Disease | rickets |
| Phenotype | C0042870|vitamin d deficiency |
| Sentences | 24 |
| PubMedID- 20711440 | vitamin d deficiency leads to osteomalacia, rickets and myopathy. |
| PubMedID- 22536773 | vitamin d deficiency leads to rickets, characterized by defective bone formation, in infants and children. |
| PubMedID- 25943362 | With regards to vitamin d knowledge, there was a significantly higher percentage of boys answering “yes” than girls in 5 out of 12 questions, 4 of which was correct [30 minute sun exposure provides enough calcium and vitamin d, about breastfeeding, and vitamin d deficiency leads to rickets in children; p-values 0.002, 0.011 0.001, and 0.001 respectively]. |
| PubMedID- 21441676 | rickets attributable to vitamin d deficiency is known to be a condition that is preventable with adequate nutritional intake of vitamin d5. |
| PubMedID- 23374621 | Not all cases of rickets can be attributed to vitamin d deficiency. |
| PubMedID- 23631804 | It is well recognized that vitamin d deficiency leads to rickets in children and osteomalacia and osteoporosis in adults[1]. |
| PubMedID- 23776846 | It is also likely same mechanisms/factors may also contribute to development of rickets in patients with vitamin d deficiency rather than dietary calcium deficiency. |
| PubMedID- 24605319 | Inadequate dietary intake of calcium and phosphorus results in the formation of weak, poorly mineralized bone, and nutritional vitamin d deficiency leads to rickets and osteomalacia (24). |
| PubMedID- 22115013 | The classical role of vitamin d in bone mineralisation is well known; vitamin d deficiency leads to rickets, osteomalacia or osteoporosis. |
| PubMedID- 23074397 | Clinical need: condition and target population vitamin d deficiency may lead to rickets in infants and osteomalacia in adults. |
| PubMedID- 22254049 | It is well-established that prolonged and severe vitamin d deficiency leads to rickets in children and osteomalacia in adults. |
| PubMedID- 23382798 | It has been well established that vitamin d is essential for ca2+ and pi transport and bone mineralization in the human body and vitamin d deficiency leads to osteoporosis, rickets, fracture and other bone diseases [6], [7]. |
| PubMedID- 21266418 | A low vitamin d level in children and adolescents is common enough to be an important public health issue globally across a range of latitudes, including the united kingdom,13 14 other european countries,15 16 17 18 19 20 the united states,21 lebanon,22 australia,23 24 and new zealand.11 25 26 overt vitamin d deficiency leads to rickets, and subclinical vitamin d deficiency may also affect bone mineralisation, as assessed by dual x ray absorptiometry.15 17 27 28 29 randomised controlled trials of vitamin d supplementation have, however, reported inconsistent results for bone densitometry measures,27 30 31 32 33 34 and therefore the effectiveness of vitamin d supplementation for improving bone density is unclear. |
| PubMedID- 23104564 | Introduction: rickets is usually attributed to vitamin d deficiency. |
| PubMedID- 22629401 | Effects on bone health are undisputed and severe vitamin d deficiency leads to rickets in children and osteomalacia in adults [7]. |
| PubMedID- 20011095 | Typically, rickets associated primarily with vitamin d deficiency presents during the first year of life. |
| PubMedID- 24049329 | In tradition, vitamin d has been associated with bone health and it is well-understood that vitamin d deficiency leads to rickets in children and osteomalacia/osteoporosis in adults. |
| PubMedID- 21107545 | During infancy and childhood, vitamin d deficiency leads to rickets and osteomalacia. |
| PubMedID- 22649517 | The classical effect of vitamin d is increased intestinal calcium absorption, and vitamin d deficiency leads to rickets in children and osteomalacia and/or osteopenia in adults [1]. |
| PubMedID- 24455278 | Several reports have incriminated vitamin d deficiency as the cause of rickets, osteomalacia, and other chronic diseases. |
| PubMedID- 22855339 | Context: inherited forms of vitamin d deficiency are rare causes of rickets and to date have been traced to mutations in three genes, vdr, encoding the 1alpha,25-dihydroxyvitamin d receptor, cyp27b1, encoding the vitamin d 1alpha-hydroxylase, and cyp2r1, encoding a microsomal vitamin d 25-hydroxylase. |
| PubMedID- 22893720 | Context: nutritional rickets is usually attributed to vitamin d deficiency. |
| PubMedID- 21569549 | vitamin d deficiency leads to rickets and osteomalacia and is also associated with breast and colorectal cancers, multiple sclerosis, dementia, rheumatoid arthritis, diabetes, parkinson's and alzheimer's diseases [6,7]. |
| PubMedID- 21606711 | While vitamin d deficiency is classically associated with rickets and osteomalacia, its effects are much more protean. |
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