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PedAM

Pediatric Disease Annotations & Medicines




Disease rheumatoid arthritis
Phenotype C0553662|juvenile idiopathic arthritis
Sentences 2
PubMedID- 23762085 Tnf-α is the key mediator of joint inflammation and bone destruction in inflammatory arthritis, such as rheumatoid arthritis, psoriatic patients with arthritis, and juvenile idiopathic arthritis.
PubMedID- 26538839 Tocilizumab is a humanized il-6 receptor monoclonal antibody [73], approved by the fda and ema for use in moderately to severely active rheumatoid arthritis, for children with polyarticular juvenile idiopathic arthritis and for the treatment of systemic juvenile idiopathic arthritis (sjia).

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