Disease | rheumatoid arthritis |
Phenotype | C0553662|juvenile idiopathic arthritis |
Sentences | 2 |
PubMedID- 23762085 | Tnf-α is the key mediator of joint inflammation and bone destruction in inflammatory arthritis, such as rheumatoid arthritis, psoriatic patients with arthritis, and juvenile idiopathic arthritis. |
PubMedID- 26538839 | Tocilizumab is a humanized il-6 receptor monoclonal antibody [73], approved by the fda and ema for use in moderately to severely active rheumatoid arthritis, for children with polyarticular juvenile idiopathic arthritis and for the treatment of systemic juvenile idiopathic arthritis (sjia). |
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