PedAM
Pediatric Disease Annotations & Medicines
| Disease | retinal degeneration |
| Phenotype | C0035334|retinitis pigmentosa |
| Sentences | 5 |
| PubMedID- 22900092 | This work also suggests that safranal could be potentially useful to retard retinal degeneration in patients with retinitis pigmentosa. |
| PubMedID- 23486466 | Recently, a d1080n mutation in irbp was found in patients with retinitis pigmentosa, a frequent cause of retinal degeneration. |
| PubMedID- 23272225 | We have demonstrated that nps can be safely used to target the photoreceptors and rpe cells without significant toxicity [21], [24], [25] and mediate improvement in the retinitis pigmentosa phenotype of the retinal degeneration slow (rds+/−) mouse model [15], [16]. |
| PubMedID- 24068865 | Our group also demonstrated that overexpression of the bip slowed the rate of retinal degeneration in rats with retinitis pigmentosa [65] (see below). |
| PubMedID- 21340525 | As such the pro347leu rhodopsin transgenic pigs have exhibited phenotypic stability through generations of outcrossing and can be used confidently in future studies of the type of retinal degeneration seen with retinitis pigmentosa. |
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