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PedAM

Pediatric Disease Annotations & Medicines




Disease retinal degeneration
Phenotype C0035333|retinitis
Sentences 4
PubMedID- 22900092 This work also suggests that safranal could be potentially useful to retard retinal degeneration in patients with retinitis pigmentosa.
PubMedID- 23272225 We have demonstrated that nps can be safely used to target the photoreceptors and rpe cells without significant toxicity [21], [24], [25] and mediate improvement in the retinitis pigmentosa phenotype of the retinal degeneration slow (rds+/−) mouse model [15], [16].
PubMedID- 21340525 As such the pro347leu rhodopsin transgenic pigs have exhibited phenotypic stability through generations of outcrossing and can be used confidently in future studies of the type of retinal degeneration seen with retinitis pigmentosa.
PubMedID- 24068865 Our group also demonstrated that overexpression of the bip slowed the rate of retinal degeneration in rats with retinitis pigmentosa [65] (see below).

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