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PedAM

Pediatric Disease Annotations & Medicines




Disease purpura
Phenotype C0040053|thrombosis
Sentences 2
PubMedID- 23130099 Vwf-dependent arteriolar platelet thrombosis is the hallmark of thrombotic thrombocytopenia purpura (ttp) and the hemolytic-uremic syndrome (hus).
PubMedID- 22022775 Lacking this cleaving activity due to mutations in the adamts13 gene or autoantibodies against the metalloprotease is associated with systemic microvascular thrombosis found in patients with thrombotic thrombocytopenic purpura (ttp).

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