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PedAM

Pediatric Disease Annotations & Medicines




Disease pulmonary hypertension
Phenotype C0040188|tic disorders
Sentences 3
PubMedID- 21490767 The accumulation of excessive echb in plasma intensifies the consumption of endogenous nitric oxide (no), resulting in several cellular dysfunctions such as vasoconstriction and systemic and pulmonary hypertension in patients with hemolytic disorders including sca.
PubMedID- 25077000 Because of a unique pathophysiology, pulmonary hypertension associated with hemolytic disorders was moved from who group i to group v ph diseases.
PubMedID- 20522578 The pathogenesis of pulmonary hypertension in hemolytic disorders is likely multifactorial, including hemolysis, impaired nitric oxide (no) bioavailability, chronic hypoxemia, chronic thromboembolic disease, chronic liver disease, and asplenia.

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