PedAM

Pediatric Disease Annotations & Medicines

Disease	pulmonary hypertension
Phenotype	C0024115\|lung diseases
Sentences	14
PubMedID- 21536179	Therapy specific for pulmonary arterial hypertension, poorly evaluated in pulmonary hypertension associated with infiltrative lung diseases, is occasionally proposed to patients with disproportionate pulmonary hypertension (mean pap > 35 mmhg), with often limited efficacy, and requiring careful follow-up (risk of increased hypoxemia) and invasive evaluation.
PubMedID- 20522579	pulmonary hypertension (ph) associated with parenchymal lung diseases is one of the most common forms of ph.
PubMedID- 21719760	Rationale: senescence of pulmonary artery smooth muscle cells (pa-smcs) caused by telomere shortening or oxidative stress may contribute to pulmonary hypertension associated with chronic lung diseases.
PubMedID- 22958673	These include interstitial and vascular lung diseases (primary forms of pulmonary hypertension and thromboembolic pulmonary diseases).
PubMedID- 20092992	pulmonary hypertension in lung diseases: survey of beliefs and practice patterns.
PubMedID- 26283756	B-lines in assessment of pulmonary hypertension in patients with interstitial lung diseases: feasibility of transthoracic lung sonographic signs.
PubMedID- 25076998	Chronic lung diseases are common causes of pulmonary hypertension.
PubMedID- 26361668	pulmonary hypertension (ph) associated with lung diseases not only is an index of poor outcome but also is an indication for bilateral procedure.
PubMedID- 23354416	pulmonary hypertension is often associated with inflammatory lung diseases, for example chronic obstructive pulmonary disease, or autoimmune diseases.
PubMedID- 22884387	Background: diffuse lung diseases promote the development of vascular changes and pulmonary hypertension (ph).
PubMedID- 20819757	Chronic hypoxia is the major mechanism implicated for the development of pulmonary hypertension in patients with lung diseases.
PubMedID- 21941650	Who group 3 includes pulmonary hypertension that occurs with chronic lung diseases such as emphysema, interstitial lung disease, and sleep disordered breathing.
PubMedID- 21266048	Background: chronic alveolar hypoxia, due to residence at high altitude or chronic obstructive lung diseases, leads to pulmonary hypertension, which may be further complicated by right heart failure, increasing morbidity and mortality.
PubMedID- 22034605	[30] patients with pulmonary hypertension associated with underlying lung diseases such as chronic obstructive pulmonary disease (copd), pulmonary fibrosis, and sarcoidosis, also are at increased risk of mortality,[31–38] and those with combined emphysema, interstitial lung disease and pulmonary hypertension have a particularly high mortality risk, with only a 60% one-year survival.

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