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PedAM

Pediatric Disease Annotations & Medicines




Disease pulmonary fibrosis
Phenotype C1800706|idiopathic pulmonary fibrosis
Sentences 4
PubMedID- 23086930 Dysregulated amphiregulin (ar) expression and egr receptor (egfr) activation have been described in animal models of pulmonary fibrosis and in patients with idiopathic pulmonary fibrosis.
PubMedID- 26395334 These effects were confirmed in both the mouse model of pulmonary fibrosis and patients with idiopathic pulmonary fibrosis, which leads to distortion of normal tissue architecture and a loss of lung function [109].
PubMedID- 21631273 Although some forms of pulmonary fibrosis may result from inflammation, idiopathic pulmonary fibrosis is currently thought to result from cell death primarily and inflammation secondarily.
PubMedID- 23029004 A study of various forms of pulmonary fibrosis, including idiopathic pulmonary fibrosis, indicated that there may be a general impairment of the production of ifn-γ in patients with pulmonary fibrosis [37].

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