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PedAM

Pediatric Disease Annotations & Medicines




Disease pulmonary fibrosis
Phenotype C0013990|emphysema
Sentences 18
PubMedID- 21787427 Because heavy cigarette smoking has been suggested to play a causative role in patients who develop emphysema combined with pulmonary fibrosis, it is not surprising that the outcomes differed between this study and our report.
PubMedID- 21787426 A response to centrilobular emphysema combined with pulmonary fibrosis results in improved survival by todd et al., fibrogenesis & tissue repair 2011, 4:6.please see related letter http://fibrogenesis.com/content/4/1/17.
PubMedID- 23662171 [52–54] combined pulmonary fibrosis with emphysema can also be associated with a severe ph phenotype.
PubMedID- 21148225 The composite physiologic index (cpi) was derived to represent the extent of fibrosis on high-resolution computed tomography (hrct), adjusting for emphysema in patients with idiopathic pulmonary fibrosis (ipf).
PubMedID- 23697753 Despite a characteristic functional and radiological profile it is still debatable whether cpfe represents a distinct syndrome or a coincidence of pulmonary fibrosis with emphysema since no common pathogenetic mechanisms have been drawn to encompass both disease entities.
PubMedID- 23734851 Background: combined idiopathic pulmonary fibrosis (ipf) with pulmonary emphysema (cpfe) is a syndrome with a characteristic presentation of upper lobe emphysema and lower lobe fibrosis.
PubMedID- 22662643 A diagnosis of combined pulmonary fibrosis with emphysema (cpfe) with interstitial pulmonary siderofibrosis (ips) was established.
PubMedID- 23819865 Smoking-related emphysema is associated with idiopathic pulmonary fibrosis and rheumatoid lung.
PubMedID- 26346712 The findings of combined pulmonary fibrosis along with emphysema have been increasingly recognized in the medical literature.
PubMedID- 24661402 The possible engraftment and differentiation of mesenchymal stem cells as a reason for the coexistence of pulmonary emphysema with pulmonary fibrosis is very exciting.
PubMedID- 21114711 The prevalence of pulmonary fibrosis combined with emphysema in patients with lung cancer.
PubMedID- 23728869 The impact of emphysema in pulmonary fibrosis.
PubMedID- 21034654 Conclusions: ptx mediated transformation of pulmonary emphysema into pulmonary fibrosis under chronic cigarette smoke exposure is associated with upregulation of beta-catenin and elevation of tgf-beta(1), implying that activation of wnt/beta-catenin signaling may be involved in the pathogenesis of pulmonary fibrosis.
PubMedID- 22235752 Variants of pulmonary fibrosis associated with emphysema have been described, and these cases have been grouped in a newly defined syndrome of combined pulmonary fibrosis and emphysema (cpfe)[8].
PubMedID- 22503074 Four distinct radiographic phenotypes were identified: isolated airways disease (54%), isolated interstitial lung disease (ild) (14%), mixed airways disease and ild (26%), and combined pulmonary fibrosis with emphysema (7%).
PubMedID- 25389350 Idiopathic pulmonary fibrosis with emphysema: evidence of synergy among emphysema and idiopathic pulmonary fibrosis in smokers.
PubMedID- 21324139 Centrilobular emphysema combined with pulmonary fibrosis results in improved survival.
PubMedID- 26495997 Objective: combined idiopathic pulmonary fibrosis with pulmonary emphysema (cpfe) is a syndrome with a characteristic presentation of upper lobe emphysema and lower lobe fibrosis.

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