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PedAM

Pediatric Disease Annotations & Medicines




Disease psoriasis
Phenotype C0042373|vascular disease
Sentences 21
PubMedID- 22500772 It has been proved that psoriasis is associated with risk of cardiovascular disease, diabetes, overweight/obesity and depression [1-5].
PubMedID- 22161801 Results of prior studies have suggested that methotrexate (mtx) may improve vascular disease in patients with psoriasis and rheumatoid arthritis.
PubMedID- 23491525 Indeed, systemic inflammation may contribute to both dm and cardiovascular disease in patients with psoriasis (31).
PubMedID- 25291969 Increased serum c-reactive protein level in japanese patients of psoriasis with cardio- and cerebrovascular disease.
PubMedID- 24320841 psoriasis is associated with cardiovascular diseases (cvd).
PubMedID- 25752901 Objectives: an increased risk for cardiovascular disease with psoriasis has been reported.
PubMedID- 26422385 psoriasis is associated with increased cardiovascular disease (cvd) in adults, but the risk profile of children with psoriasis remains to be fully characterized.
PubMedID- 26300652 There is overwhelming evidence on the higher risk of cardiovascular diseases in patients with psoriasis as a result of hyperlipidemia, which is more common in these patients.
PubMedID- 26121943 What is more, a number of studies and observations confirm an increased occurrence of the standard atherosclerosis risk factors and/or metabolic syndrome as well as cardiovascular diseases in patients with psoriasis [9, 18, 22, 27, 35, 45].
PubMedID- 24238156 psoriasis was associated with cardiovascular disease in total (odds ratio [or] 1.4; 95% confidence interval [ci] 1.2-1.7), ischemic heart disease (or 1.5; 95% ci 1.2-1.9), peripheral vascular disease (or 1.5; 95% ci 1.2-1.8), atherosclerosis (or 1.1; 95% ci 1.1-1.2), diabetes (or 1.9; 95% ci 1.5-2.5), hypertension (or 1.8; 95% ci 1.6-2.0), dyslipidemia (or 1.5; 95% ci 1.4-1.7), obesity by body mass index (or 1.8; 95% ci 1.4-2.2), obesity by abdominal fat (or 1.6; 95% ci 1.2-2.3), and the metabolic syndrome (or 1.8; 95% ci 1.2-2.8), but not associated with cerebrovascular disease (or 1.1; 95% ci 0.9-1.3) and cardiovascular mortality (or 0.9; 95% ci 0.4-2.2).
PubMedID- 23058814 Background: psoriasis has been associated with cardiovascular diseases, but its relationship to markers of subclinical atherosclerosis has not been fully elucidated.
PubMedID- 25622660 A further evidence of a link between, obesity, inflammation and cardiovascular diseases in patients with psoriasis is provided by several studies reporting a correlation between pasi score and increased of c-reactive protein (crp) levels [20], an acute phase protein significantly associated with obesity, representing the most sensitive markers of inflammation and an independent risk for cardiovascular disease.
PubMedID- 24161194 An interdisciplinary approach is needed to find the necessary steps beyond classic risk reduction and detection of early cardiovascular disease in patients with psoriasis, as well as to develop a cardiovascular disease preventive regimen.
PubMedID- 22963528 We therefore examined the rate of cardiovascular disease events in patients with severe psoriasis treated with systemic anti-inflammatory drugs.
PubMedID- 24599540 A combinational therapy for patients with severe psoriasis associated with cardiovascular disease.
PubMedID- 24504802 Hypercholesterolemia is a major risk factor for cardiovascular disease, and patients with psoriasis or psoriatic arthritis (psa) have been shown to have elevated cholesterol levels.
PubMedID- 24082881 A number of studies suggest a high prevalence of cardiovascular risk factors as well as cardiovascular diseases in psoriasis patients.
PubMedID- 23636854 Aortic arterial stiffness is a moderate predictor of cardiovascular disease in patients with psoriasis vulgaris.
PubMedID- 24860744 [14] increased mortality from cardiovascular disease in patients with severe psoriasis has been documented and psoriasis may be an independent risk factor for myocardial infarction, especially in young patients.
PubMedID- 23006590 These findings emphasize the increased burden of cardiovascular disease in patients with psoriasis and they call for further studies in this area of research.
PubMedID- 25896794 Therefore, while tnf-alpha inhibitors were shown to reduce development of cardiovascular disease in patients with psoriasis [27], no evidence regarding such an effect is available in pemphigus.

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