PedAM
Pediatric Disease Annotations & Medicines
| Disease | proteinuria |
| Phenotype | C0027726|nephrotic syndrome |
| Sentences | 49 |
| PubMedID- 24317117 | Circulating angiopoietin-like 4 links proteinuria with hypertriglyceridemia in nephrotic syndrome. |
| PubMedID- 21132650 | A 47-year-old woman was referred to our unit for evaluation of proteinuria associated with nephrotic syndrome. |
| PubMedID- 21904677 | The development of nephrotic-range proteinuria, without full nephrotic syndrome, is consistent with the role of b4 as a minor podocyte integrin. |
| PubMedID- 26551740 | Focal segmental glomerulosclerosis (fsgs) is a pathologic entity that is a common cause of nephrotic syndrome with severe proteinuria in both adults and children. |
| PubMedID- 23162265 | The limited evidence suggested that dfz appeared to be equally effective in inducing remission or decreasing proteinuria in patients with nephrotic syndrome. |
| PubMedID- 23670304 | Podocyte loss correlated with lower selectivity of proteinuria in patients with minimal change nephrotic syndrome and focal segmental glomerulosclerosis (r = -0.90; p < 0.001). |
| PubMedID- 22661128 | Because of a lack of ultrastructural detail (the electron microscopy was not invented until 50 years later) and limited by only a superficial insight in renal inflammatory processes, the authors failed to recognize the glomerulus as the origin of proteinuria in patients with the nephrotic syndrome and placed too much emphasis on tubular reabsorption patterns coined lipoid nephrosis. |
| PubMedID- 21534236 | Clinically, lg is characterized by proteinuria generally associated with nephrotic syndrome and progressive renal insufficiency. |
| PubMedID- 23295293 | Nephropathy in fs consists in nephrotic syndrome (ns) with proteinuria that begins early in childhood and progressively increases with age, mainly due to nonspecific focal and segmental glomerular sclerosis (fsgs). |
| PubMedID- 24533189 | It is well known that malignancy causes proteinuria with or without nephrotic syndrome [1–3]. |
| PubMedID- 26511325 | Furthermore, a systemic hyperosmolar state from proteinuria and hypoalbuminemia associated with nephrotic syndrome contributes to the leakage of fluid into the suprachoroidal space [6]. |
| PubMedID- 24860853 | Although sirolimus is not generally thought to be nephrotoxic, it can be associated with proteinuria, which can lead to nephrotic syndrome and subsequent kidney injury (25). |
| PubMedID- 19773419 | Recurrence of nephrotic-range proteinuria in patients with idiopathic nephrotic syndrome (ins) and focal and segmental glomerulosclerosis (fsgs) on native kidneys is associated with poor graft survival. |
| PubMedID- 24886259 | Mutations in the podocin gene cause severe structural podocyte alterations and massive proteinuria leading to nephrotic syndrome [22]. |
| PubMedID- 24282415 | Due to persistent activation of the chronic inflammatory process, whether clinically manifested orsubclinically, excess saa is deposited in the form of fibrils in various organs, particularly the kidneys, with the consequent progressive development of severe proteinuria, leading to nephrotic syndrome and kidney failure. |
| PubMedID- 24294005 | At the time of biopsy, six (75%) of them had nephrotic syndrome with mean proteinuria of 3.8 ± 2.24 g/day. |
| PubMedID- 23275781 | In the following months, the serum creatinine increased up to 2.2–2.4 mg/dl (egfr 27.5 ml/min/1.73 m2), blood pressure control continued to be poor, and there was a persistence of edema and nephrotic syndrome with proteinuria of 8 g/day. |
| PubMedID- 22909024 | They are characterized by heavy proteinuria, with nephrotic syndrome and impaired renal function in half of the patients. |
| PubMedID- 20649959 | As previously reported [3,9], a single injection of pan (150 mg/kg body wt) to rats induced a marked nephrotic syndrome with severe proteinuria (~10 g/mmol creatinine) and decreased sodium excretion (< 5 mmol/mmol creatinine) (figure 4a). |
| PubMedID- 21844386 | Mice developed a nephrotic syndrome with severe edema, proteinuria, hypoalbuminemia, and elevated cholesterol and triglycerides. |
| PubMedID- 25667774 | Further evaluations including renal biopsy are necessitated in settings of sudden onset heavy proteinuria with or without nephrotic syndrome [135, 136].treatment of haematuria includes bed rest, hydration, and blood transfusion if indicated in events of a significant blood loss. |
| PubMedID- 26054711 | Conclusions: serum half-life of rtx can be extremely short, partly due to excessive urinary losses in therapy-resistant nephrotic syndrome with non-selective proteinuria, as seen in our patient. |
| PubMedID- 21403411 | Although a moderate degree of proteinuria is common in patients with igan, nephrotic syndrome is considered uncommon in these patients.3 the course of igan is variable, and 15% to 40% of patients progress to end-stage renal disease over a period of 10 to 20 years.4 the pathogenesis of igan is complex and not completely understood. |
| PubMedID- 23559294 | Background: collapsing glomerulopathy is a cause of nephrotic syndrome with massive proteinuria secondary to podocyte proliferation and glomerular collapse. |
| PubMedID- 20483511 | Diagnostic strategy relies on the clinical presentation: acute renal failure, chronic kidney disease, glomerular proteinuria with or without nephrotic syndrome, tubular proteinuria, hydroelectrolytic disorders. |
| PubMedID- 25874088 | Here we report an association between collapsing glomerulopathy and an acute ebv syndrome, manifesting itself clinically as nephrotic syndrome with massive proteinuria, hypoalbuminemia, anasarca and hypercholesterolemia. |
| PubMedID- 23479095 | Presenting features comprise any of the following: proteinuria (sometimes with the nephrotic syndrome), haematuria, hypertension and renal failure. |
| PubMedID- 25557779 | nephrotic syndrome (ns), the association of gross proteinuria, hypoalbuminaemia, edema, and hyperlipidemia, can be clinically divided into steroid-sensitive (ssns) and steroid-resistant (srns) forms. |
| PubMedID- 25688242 | Lupus nephritis is a frequent and potentially serious complication among patient with systemic lupus erythematosus whose clinical manifestations are varied being the most common manifestations proteinuria (commonly leading to nephrotic syndrome), microscopic hematuria, and reduced gfr. |
| PubMedID- PMC4044283 | Subsequently, the patient developed proteinuria with nephrotic syndrome. |
| PubMedID- 26447100 | Background: proteinuria leading to nephrotic syndrome is a rare adverse event arising from treatment with bevacizumab. |
| PubMedID- 24798567 | Rituximab, a chimeric monoclonal antibody against the cd20 antigen on b cells, safely reduced proteinuria in patients with nephrotic syndrome secondary to membranous nephropathy, minimal change disease, or focal segmental glomerulosclerosis. |
| PubMedID- 25657979 | proteinuria with or without nephrotic syndrome is the most common clinical finding, and this finding in elderly patients should be a formal indication of renal biopsy as a diagnostic tool. |
| PubMedID- 26395882 | In the first year of life, 66 % of the patients suffering from hypoalbuminemia and severe proteinuria are diagnosed with genetic nephrotic syndrome (gns) [1]. |
| PubMedID- 24319525 | It manifests clinically as proteinuria with or without nephrotic syndrome, immune-complex glomerulonephritis, progressive renal failure, impaired urinary concentration ability, incomplete distal tubular acidosis and haematuria [2]. |
| PubMedID- 24749114 | A year after the beginning of the symptoms she sought medical attention: a diagnosis of nephrotic syndrome with proteinuria >10 g/l was made. |
| PubMedID- 23759297 | Results: all patients presented with proteinuria, associated with nephrotic syndrome (41%), hematuria (73%), and hypertension (70%). |
| PubMedID- 23006339 | In september 2010, her nephrotic syndrome returned with proteinuria (9.5 g/d), anasarca (11.3 kg weight gain), hyperlipidemia (total cholesterol 332 mg/dl, ldl 229 mg/dl, triglycerides 270 mg/dl), and a cr of 1.9 mg/dl. |
| PubMedID- 23197960 | In conclusion, bilateral rae is an alternative, effective, rapid, and safe procedure for the treatment of heavy proteinuria with nephrotic syndrome. |
| PubMedID- 25558821 | Immunosuppressive agents should be used for patients who suffer from refractory proteinuria or complications associated with nephrotic syndrome. |
| PubMedID- 22461531 | Results: initially, 95% of patients had nephrotic syndrome with proteinuria of 3-12 g per 24 hours, creatinine levels of 0.6-9.6 mg/dl, positive lupus serologies, and normal complement levels in 63%. |
| PubMedID- 21502717 | Renal amyloidosis is typically characterized by nephrotic syndrome, often with massive proteinuria and refractory peripheral edema. |
| PubMedID- 23983784 | nephrotic syndrome shows symptoms of hypoalbuminemia, hyperlipidemia, persistent proteinuria, and abnormal renal function. |
| PubMedID- 20419132 | Mutations of the nephrin gene lead to congenital nephrotic syndrome with proteinuria and renal failure [12]. |
| PubMedID- 23476687 | Mutations in the podocin gene cause severe structural podocyte alterations and massive proteinuria leading to nephrotic syndrome [25]. |
| PubMedID- 26203254 | Renal toxicity is an uncommon ae of all nsaids, and risk is elevated in those who have preexisting severe hepatic or renal dysfunction, nephrotic syndrome with high-level proteinuria, older age, diabetes, hypertension, congestive heart failure, or dehydration. |
| PubMedID- 23087561 | [1] clinical manifestations may range from nephrotic syndrome (in 30–50% of patients), <1 g/day proteinuria (~25% patients), progressive renal insufficiency (in approximately 70% of patients), and hypertension (in more than 80% of the patients) among others. |
| PubMedID- 25886386 | Studies also showed that as-iv can attenuate podocyte injury and ameliorate proteinuria in adults with idiopathic nephrotic syndrome [16]. |
| PubMedID- 21497573 | Renal manifestations are frequent, mostly characterized by heavy proteinuria, with nephrotic syndrome and renal failure in more than half of the patients at diagnosis. |
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