PedAM

Pediatric Disease Annotations & Medicines

Disease	proteinuria
Phenotype	C0022658\|renal disease
Sentences	19
PubMedID- 22973348	This study was a self-controlled clinical trial conducted in several private nephropathy clinics from september 2008 to june 2010 to assess the effect of pioglitazone on the rate of proteinuria in patients with existing non-diabetic renal disease.15 before the study, ethical approval was obtained from the local research ethics committee at school of medicine, isfahan university of medical sciences.
PubMedID- 24453508	Other criteria supporting a diagnosis of preeclampsia included an elevated serum alanine aminotransferase (alt) concentration (>70 units/l), increasing proteinuria in patients with pre-existing renal disease, persistent severe headaches, or epigastric pain.
PubMedID- 21694934	Reduction of proteinuria is associated with stabilization of renal disease or slowing of its progression.
PubMedID- 23841057	In particular, end-stage renal disease, with proteinuria and progressive renal failure, is a major cause of morbidity and mortality in fd.
PubMedID- 24629167	Mortality risk ratios for cerebrovascular diseases and renal diseases of the exposed proteinuria group and for ischemic heart diseases, digestive diseases and renal diseases of the exposed glucosuria group were significantly increased in women (table 6).
PubMedID- 25587546	Raas blockers are the first line drugs for the treatment hypertension associated with diabetes and have been widely used in everyday clinical practice for the purpose of reducing proteinuria in patients with various renal diseases.
PubMedID- 21753253	Hiv-associated renal disease with overt proteinuria has been associated with poorer outcomes and increased mortality.
PubMedID- 20842993	Persistent proteinuria may be associated with more serious renal diseases.
PubMedID- 21738895	It has also been reported that aldosterone receptor blocker treatment can reduce proteinuria in patients with chronic renal disease who did not respond to acei therapy [11].
PubMedID- 26105412	Injury of parietal epithelial cells in glomeruli, the podocytes, is the initiating cause of many renal diseases, leading to proteinuria with possible progression to glomerulosclerosis.
PubMedID- 21415920	It is unlikely that our patients had renal disease because none of them had proteinuria or a plasma creatinine concentration >120 μmol/l.
PubMedID- 26019845	Paricalcitol decreases proteinuria in patients with proteinuric renal disease [30–32].
PubMedID- 22253810	We also evaluated the usefulness of the mt-mouse as an animal model of renal disease with proteinuria, such as congenital nephrotic syndrome (cns) [17], [22], and the potential of administering neu5ac as a therapeutic strategy to prevent renal disorders resulting from hyposialylation.
PubMedID- 26089878	Diabetic nephropathy was defined as diabetic renal disease with proteinuria, with or without elevation of serum creatinine (cr) levels [19].
PubMedID- 24159603	While novel agonists of antioxidant pathways and other approaches show promise in diabetic nephropathy [25], the development of overt proteinuria typically leads to progressive renal disease and the eventual need for renal replacement therapy [2].
PubMedID- 20828590	Injury to the podocytes is the initiating cause of many renal diseases, leading to proteinuria with possible progression to end-stage renal disease.
PubMedID- 22675377	It has been recently found that nephrin expression level is reduced in experimental animal models and human-acquired renal disease with proteinuria [39, 40].
PubMedID- 23209764	Residual proteinuria is tightly associated with progression of renal disease, and thus additional treatments are needed for this group of patients [3].
PubMedID- PMC4034014	Several studies have been carried out on the shrob model, considered to be useful for investigating the interactions of metabolic abnormalities that constitute syndrome x, including genetic obesity, genetically determined hypertension, and hyperinsulinemia, hypertriglyceridemia and renal disease with proteinuria [49,50,51,52,53,54].

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