PedAM
Pediatric Disease Annotations & Medicines
| Disease | proteinuria |
| Phenotype | C0022658|kidney disease |
| Sentences | 56 |
| PubMedID- 26325557 | Importance: steroidal mineralocorticoid receptor antagonists, when added to a renin-angiotensin system blocker, further reduce proteinuria in patients with chronic kidney disease but may be underused because of a high risk of adverse events. |
| PubMedID- 21782142 | Beyond being an important diagnostic marker, proteinuria is associated with kidney disease progression in both dogs and cats: the greater the magnitude of the proteinuria, the greater the risk of renal disease progression and mortality. |
| PubMedID- 20671225 | Conclusions: in chronic kidney disease patients with residual proteinuria despite combined angiotensin-converting enzyme inhibitor and angiotensin receptor blockade therapy, add-on fluvastatin does not affect urinary proteins, but further reduces serum lipids and is safe. |
| PubMedID- 22607020 | We investigated the relationship between cys-c and proteinuria in patients with chronic kidney disease. |
| PubMedID- PMC3991017 | More importantly, spironolactone has been reported to further decrease proteinuria in patients with chronic kidney disease already on chronic treatment with ace inhibitors suggesting that aldosterone antagonists may also add to the renoprotective effect of raas inhibition in humans [2,6,7,8]. |
| PubMedID- 26557728 | Two previous retrospective analyses by our group suggested a role for uteroplacental flows and for two serum biomarkers, soluble fms-like tyrosine kinase 1 (sflt-1) and placental growth factor (plgf), in distinguishing between pe and chronic kidney disease (ckd) in patients with hypertension and proteinuria during pregnancy [16, 17]. |
| PubMedID- 22073844 | As a pleiotropic effect, paricalcitol reduces proteinuria in patients with chronic kidney disease stages 2-4. |
| PubMedID- 24052467 | Risk factors for kidney diseases and awareness of blood pressure and proteinuria in general population and in high school students: italian report for world kidney days 2012-2013. |
| PubMedID- 22701173 | In chronic renal disease, a low dietary protein content slows the progression of kidney disease, especially in patients with proteinuria and decreases the supply of phosphorus, which has been directly related with progression of kidney disease and with patient survival. |
| PubMedID- 21251050 | Hepatocyte growth factor (hgf) has the therapeutic potential to improve renal fibrosis and proteinuria in rodents with chronic kidney disease. |
| PubMedID- 22917002 | By studying 189 non diabetic ckd patients, the present study clearly shows that aliskiren reduced proteinuria in patients with non-dm chronic kidney disease who were receiving arbs. |
| PubMedID- 23497267 | Such studies have demonstrated associations of a resistive index to proteinuria in patients with chronic kidney disease with and without diabetes mellitus; [30] to albuminuria and also a measure of aortic stiffness (brachial-ankle) in 150 patients with type 2 diabetes mellitus; [31] and in patients with hypertension, a modest increase in renal resistive index was associated with a greater adjusted relative risk of albuminuria [32]. |
| PubMedID- 22386936 | Statins have been shown to ameliorate renal function and reduce proteinuria in patients with chronic kidney disease. |
| PubMedID- 22333173 | Objective: to evaluate the efficacy and safety of high-dose irbesartan in the treatment of mild and moderate proteinuria in patients with chronic kidney disease (ckd). |
| PubMedID- 23585423 | Objective: to evaluate the efficacy of enalapril treatment on decline in glomerular filtration rate and reduction in proteinuria in children with chronic kidney disease (ckd). |
| PubMedID- 23167771 | We evaluated the antiproteinuric effect of pct in non-dialysis chronic kidney disease (ckd) patients with proteinuria greater than 0.5 g/24 h persisting despite anti-ras therapy titrated to minimize proteinuria in the absence of adverse effects. |
| PubMedID- 22019331 | Background: vitamin d has shown efficacy in the reduction of proteinuria in patients with chronic kidney disease. |
| PubMedID- 23509710 | Paricalcitol has recently been shown to reduce proteinuria in patients with diabetic kidney disease [4–6, 12, 14]. |
| PubMedID- 21799148 | Increasing proteinuria correlated with progression of kidney disease. |
| PubMedID- 20703230 | The principal means for reducing proteinuria in patients with chronic kidney disease are strong blockade of the renin-angiotensin system and strict regulation of blood pressure (bp). |
| PubMedID- 22619886 | An open label, randomized controlled study of oral calcitriol for the treatment of proteinuria in patients with diabetic kidney disease. |
| PubMedID- 26151753 | However, the effects of statins on renal outcomes, including decline in estimated glomerular filtration rate (egfr) and proteinuria in patients with chronic kidney disease (ckd), are controversial. |
| PubMedID- 23551149 | Results: ten family members had chronic kidney disease with late-onset gross proteinuria and a variable course of declining renal function, starting in the fourth decade of life. |
| PubMedID- 23238659 | Objective: to examine racial/ethnic differences in the prevalence of diabetic kidney disease (dkd), with and without proteinuria, in an outpatient health care organization. |
| PubMedID- 24965167 | Impact of combined losartan/hydrochlorothiazide on proteinuria in patients with chronic kidney disease and hypertension. |
| PubMedID- 21365885 | [is morning urinary protein-to-creatinine ratio a reliable estimator of 24-hour proteinuria in patients with kidney diseases. |
| PubMedID- 23326865 | In this exploratory short-term study, we demonstrated that treatment with a renin inhibitor, aliskiren, significantly reduced proteinuria in patients with nondiabetic chronic kidney diseases. |
| PubMedID- 25880876 | Research shows that dietary interventions focused on sodium reduction lower blood pressure, decrease extracellular fluid volume and reduce proteinuria in patients with kidney disease [31]. |
| PubMedID- 22903660 | Progressive loss of the filtration barrier allows excessive proteinuria, which ultimately leads to end-stage kidney disease (eskd). |
| PubMedID- 23510329 | In diabetics and in the presence of kidney disease, especially with pathological proteinuria, renin-angiotensin-aldosterone system blockers should be preferred[99,100]. |
| PubMedID- 24708763 | Among 1,781 participants with ckd stages 2–4 from the modification of diet in renal disease study, compared with serum bicarbonate levels ≥26 meq/l, levels ≤20 meq/l were associated with a higher risk of kidney failure (hazard ratio (hr) 2.22 (95% ci, 1.83-2.68)) while adjusting for demographic and cardiovascular disease factors, serum albumin, proteinuria, and cause of kidney disease [12]. |
| PubMedID- 20605301 | In analyses adjusted for demographic and cardiovascular disease factors, serum albumin level, proteinuria, and cause of kidney disease, compared with quartile 4, quartile 1 was associated with a 2.22 hr (95% ci, 1.83-2.68) of kidney failure; 1.39 hr (95% ci, 1.07-1.18) of all-cause mortality; and 1.36 hr (95% ci, 1.15-1.62) of the composite outcome. |
| PubMedID- 22737779 | proteinuria among patients with chronic kidney disease: a performance measure for improving patient outcomes. |
| PubMedID- 22045242 | Injury to the podocyte results in proteinuria and often leads to progressive kidney disease. |
| PubMedID- 24867154 | Assessment of proteinuria in patients with chronic kidney disease stage 3: albuminuria and non-albumin proteinuria. |
| PubMedID- 25412689 | We suggest that all patients at the time of hiv diagnosis should carry out a screening for kidney disease with egfr assessment, proteinuria, and urine analysis. |
| PubMedID- 23644107 | Objective: to evaluate the clinical efficacy of syndrome differentiation-based treatment with traditional chinese medicine (tcm) versus losartan therapy in addition to basic treatment for management of proteinuria in patients with chronic kidney disease. |
| PubMedID- 26587302 | His past medical history was otherwise notable for hypertension, type ii diabetes mellitus, atrial fibrillation, and chronic kidney disease with bence jones proteinuria (k-flc proteinuria of 691 mg/dl). |
| PubMedID- 26528285 | Supplementation with vitamin d in the general population has shown fracture prevention, suggested benefit in cardiovascular health, colorectal cancer prevention and reduction of proteinuria in patients with chronic kidney disease (20, 21). |
| PubMedID- 21852669 | Whether central measures of bp or vascular stiffness are associated with increased risk of proteinuria in patients with chronic kidney disease (ckd) is unknown. |
| PubMedID- 26177311 | Our findings are consistent with several previous studies, indicating that circulating tnfrs were significantly correlated with the egfr or proteinuria in patients with various kidney diseases [14–17,26,27]. |
| PubMedID- 23894629 | This has been proposed as a major mechanism for the progression of kidney disease in patients with proteinuria [31]–[34]. |
| PubMedID- 24384547 | Olmesartan is more effective than other angiotensin receptor antagonists in reducing proteinuria in patients with chronic kidney disease other than diabetic nephropathy. |
| PubMedID- 22934182 | proteinuria correlates with kidney disease progression and cardiovascular mortality. |
| PubMedID- 23691273 | As glomerulosclerosis becomes more extensive, the gfr starts to decrease and nonselective proteinuria may result leading to chronic kidney disease and subsequently esrd [11–13]. |
| PubMedID- 24843543 | Several smaller randomized trials have indicated that paricalcitol reduces proteinuria in patients with chronic kidney disease. |
| PubMedID- 20490905 | Aldosterone receptor antagonists reduce proteinuria in patients with proteinuric kidney disease who are already receiving ace inhibitors or arbs [61]. |
| PubMedID- 25018969 | Association of proteinuria with race, cause of chronic kidney disease, and glomerular filtration rate in the chronic kidney disease in children study. |
| PubMedID- 23552860 | We compared the therapeutic effects of fasudil on the spontaneously hypercholesterolemic (shc) rat, a model of chronic kidney disease (ckd) with proteinuria, with those of the angiotensin receptor blocker olmesartan (ol) by paying attention to the proteinuria and the macrophage phenotype. |
| PubMedID- 25788940 | However, proteinuria can occur because of other kidney diseases besides hbv-related gn (hbv-gn). |
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