PedAM
Pediatric Disease Annotations & Medicines
| Disease | proteinuria |
| Phenotype | C0017661|iga nephropathy |
| Sentences | 23 |
| PubMedID- 23741418 | Emerging clinical and animal studies have demonstrated that vitamin d and its analog reduce proteinuria in patients with iga nephropathy [2], non-dialysed chronic kidney disease stage 4–5 [3], [4], diabetic nephropathy [5], and animal models such as subtotally nephrectomized model [6], diabetic nephropathy model [7], adriamycin-induced nephropathy [8], puromycin-induced nephropathy [9], [10]. |
| PubMedID- 20594038 | The authors measured the extent of foot process effacement in 100 iga nephropathy cases with proteinuria and correlated it with the amount of proteinuria. |
| PubMedID- 23713873 | Calcitriol (0.5 microg calcitriol twice per week) has been effective in decreasing proteinuria in patients with iga nephropathy. |
| PubMedID- 24721885 | Conclusions: the findings in this cohort and previous studies suggest that rare cases of mild iga nephropathy with nephrotic range proteinuria exhibit a clinical presentation, biopsy findings, treatment response, and outcome more typical of iga nephropathy with superimposed minimal change disease. |
| PubMedID- 23331443 | Conclusion: for early iga nephropathy patients with minimal proteinuria, normal blood pressure, and normal renal function, treatment with 2.5 mg/daily of ramipril for 5 years does not offer any benefit. |
| PubMedID- 24707402 | Before the eradication therapy the mean proteinuria of patients with mn, iga nephropathy and fsgs were 2.42 +/- 3.24 g/day, 2.12 +/- 1.63 g/day and 1.80 +/- 1.32 g/day, respectively. |
| PubMedID- 22456060 | Some iga nephropathy (igan) patients with massive proteinuria showed resistance to steroids and/or cytotoxic immunosuppressants based on the supportive therapy with renin- angiotensin system blockade. |
| PubMedID- 23557791 | Aims: both steroid pulse (sp) monotherapy and the combination of tonsillectomy and sp therapy (tsp) are effective for achieving clinical remission (cr), defined as negative hematuria and proteinuria, in patients with iga nephropathy (igan). |
| PubMedID- 20826744 | Conclusions: among patients with primary glomerulopathy and nephrotic-range proteinuria, normoalbuminaemia is associated with iga nephropathy. |
| PubMedID- 23977072 | In another report, among 121 iga nephropathy patients with proteinuria ≥1 g/day at presentation or during follow-up period, reduced proteinuria group (in which proteinruia was decreased to <1 g/day at last follow-up) showed better outcome compared to persistent proteinuria group and showed similar renal outcome as in low proteinuria group [7]. |
| PubMedID- 23326865 | In two small studies, the addition of aliskiren to arb was shown to decrease proteinuria in subjects with iga nephropathy and various forms of primary glomerulonephritis [13, 14]. |
| PubMedID- 22086123 | Reported on the natural history of mild or early-stage iga nephropathy in patients with proteinuria <0.4 g/day over an observation period of 7 years [5]. |
| PubMedID- 21533280 | Recently, cheng's review [46] illustrated that glucocoticoids significantly induced a protection of renal function and a reduction of proteinuria in patients with iga nephropathy. |
| PubMedID- 23197956 | Successful treatment of adult iga nephropathy with nephrotic-level proteinuria by combination therapy including long-term coadministration of mizoribine. |
| PubMedID- 22019331 | Conclusions: the addition of calcitriol to a renin-angiotensin system inhibitor resulted in a safe decrease in proteinuria in patients with iga nephropathy. |
| PubMedID- 23675422 | The primary objective of the present study is to evaluate the safety and short-term efficacy of aliskiren, a direct renin inhibitor, on proteinuria reduction in patients with iga nephropathy. |
| PubMedID- 23049672 | Oral calcitriol treatment reduced proteinuria in patients with iga nephropathy [172]. |
| PubMedID- 20843592 | Conclusions: thujone-free wormwood with its favorable safety profile can be an alternative supplement to manage proteinuria in patients with iga nephropathy. |
| PubMedID- 26289088 | Background: sometimes, acute and progressive proteinuria increases occur in patients with iga nephropathy (igan) after favorable long-term clinical courses of >10 years, but their clinical and histological characteristics are not well understood. |
| PubMedID- 21655166 | [2122] the ii genotype has been reported to be associated with more favorable prognosis and decreased proteinuria in patients with iga nephropathy. |
| PubMedID- 23502465 | Reported a down-regulation of nestin expression in fsgs, mn and iga nephropathy with proteinuria, and the glomerular nestin expression levels correlated inversely with the 24-hour urine protein results [11]. |
| PubMedID- 26239462 | Urinary ngal levels also correlated with the degree of proteinuria in patients with iga nephropathy [16] and membranous nephropathy [14,15]. |
| PubMedID- 26527894 | Most of the study population included diabetic nephropathy, lupus nephropathy, and iga nephropathy with persistent proteinuria, and received corticosteroid therapy, confirming the need for validating gfr equations in this setting. |
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