PedAM
Pediatric Disease Annotations & Medicines
| Disease | prostate cancer |
| Phenotype | C0028754|obesity |
| Sentences | 34 |
| PubMedID- 22469146 | Background: obesity is associated with prostate cancer aggressiveness and mortality. |
| PubMedID- 20033185 | Objective: several reports found that obesity was associated with prostate cancer (pc) aggressiveness among men treated with radical prostatectomy or radiotherapy. |
| PubMedID- 26181184 | Objective: to determine whether the association of obesity with prostate cancer risk differs between african american and non-hispanic white men and whether obesity modifies the excess risk associated with african american race. |
| PubMedID- 23710344 | They were able to estimate how obesity increases the risk of prostate cancer and that despite the overall decreases in prostate cancer mortality, the declines were limited by the increase in obesity. |
| PubMedID- 21266978 | This might imply that abdominal fat rather than general obesity may be associated with prostate cancer risk. |
| PubMedID- 20404514 | Findings from epidemiological studies correlating obesity, the sources of dietary fat and prostate cancer (pca) are conflicting. |
| PubMedID- 25877612 | Background: recent evidence suggests a particular role for obesity in prostate cancer (pca) progression. |
| PubMedID- 25261967 | We examined the association between obesity and risk of low- and high-grade prostate cancer in reduce, in which biopsies were largely independent of psa. |
| PubMedID- 25903805 | Background: there is evidence that obesity is associated with an aggressive prostate cancer (pc). |
| PubMedID- 26387087 | Our aim was to use genetic variation in height and body mass index (bmi) as unconfounded exposures to investigate the causal associations of obesity and stature with prostate cancer risk and outcomes (mendelian randomization [20]). |
| PubMedID- 22249290 | Background: emerging data suggest that obesity increases the risk of aggressive prostate cancer (pc), but the mechanisms underlying this relationship remain to be fully elucidated. |
| PubMedID- 22921964 | This provides further support for the idea that obesity is biologically associated with prostate cancer progression. |
| PubMedID- 24240026 | Incidence of skeletal metastases and death from prostate cancer greatly increases with age and obesity, conditions which increase marrow adiposity. |
| PubMedID- 24272675 | Among other findings, it was proven that obesity increases the risk of more aggressive prostate cancer [2], prostate enlargement in men with localized prostate cancer [3], and developing benign prostate hyperplasia (bph) [4]. |
| PubMedID- 21242331 | Impact: the inverse association of obesity with prostate cancer diagnosis may be at least partly due to detection bias, which is due to larger prostate volumes and psa hemodilution in obese men. |
| PubMedID- 25737954 | While some studies show a modest increase in the risk of high grade prostate cancer with obesity [2], others suggest no significant association [3]. |
| PubMedID- 21369380 | [9] some studies in western literature have shown an association of high-grade prostate cancer with central obesity, hyperinsulinemia, and dyslipidemia. |
| PubMedID- 20697428 | The absence of any significant association between obesity and diabetes with prostate cancer in this population has been reported previously(21). |
| PubMedID- 26373570 | Herein, we summarize epidemiologic and preclinical evidence for an association between obesity and increased risk of breast and prostate cancer incidence and mortality. |
| PubMedID- 21458309 | Conclusions: although obesity has been associated with more aggressive prostate cancer, bmi does not appear to have statistically significant influence on the rate and location of psm in rlrp. |
| PubMedID- 20800152 | Background: previous studies suggest that obesity is associated with higher prostate cancer progression and mortality despite an association with lower prostate cancer incidence. |
| PubMedID- 26181179 | Difference in association of obesity with prostate cancer risk between us african american and non-hispanic white men in the selenium and vitamin e cancer prevention trial (select). |
| PubMedID- 20507889 | Although obesity is not associated with prostate cancer incidence overall, it is associated with fatal and aggressive disease [6]. |
| PubMedID- 21258401 | Although the underlying biological mechanism is not fully understood, it has been speculated that the association of obesity with increasing prostate cancer aggressiveness may be resulted from endocrine derangements (irigaray et al., 2007; o’malley and taneja, 2006). |
| PubMedID- 21397927 | Circulating levels of adiponectin, a protein involved in insulin resistance and obesity, have been associated with prostate cancer risk. |
| PubMedID- 23820091 | We evaluated the association between obesity and mets with prostate cancer pathology and surgical and functional outcomes. |
| PubMedID- 22690216 | Leptin may be a potential link between obesity and risk of progression of prostate cancer. |
| PubMedID- 25822612 | While evidence is accumulating about the association of obesity with prostate cancer aggressiveness and poor clinical outcomes [27], little is known about any influence of body composition on clinical benefits of specific therapies for prostate cancer. |
| PubMedID- 24769031 | However, only mild obesity was significantly associated with prostate cancer specific survival (hr 1.51, p = 0.040), whereas moderate/severe obesity was not (hr 1.58, p = 0.356). |
| PubMedID- 20367635 | Objective: to analyse the relationship between african american (aa) race and obesity in men with prostate cancer. |
| PubMedID- 21198939 | Relationship between prostate-specific antigen and obesity in prostate cancer screening: analysis of a large cohort in japan. |
| PubMedID- 24865433 | Corpulence is the crucial factor: association of testosterone and/or obesity with prostate cancer stage. |
| PubMedID- 23009325 | Recent studies demonstrated that obesity is associated with prostate cancer aggressiveness and prognosis. |
| PubMedID- 24292212 | Conclusions: these results suggest that obesity is linked with poorer prostate cancer prognosis primarily in men with tumors harboring the gene fusion tmprss2:erg. |
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