PedAM
Pediatric Disease Annotations & Medicines
| Disease | prostate cancer |
| Phenotype | C0011860|type 2 diabetes |
| Sentences | 9 |
| PubMedID- 23193118 | Association of type 2 diabetes susceptibility variants with advanced prostate cancer risk in the breast and prostate cancer cohort consortium. |
| PubMedID- 26559055 | Although most studies conducted in western countries suggest a lower risk of prostate cancer in patients with type 2 diabetes mellitus [13], studies conducted in taiwan and china do not conclude similarly and on the contrary support a higher risk of prostate cancer in patients with type 2 diabetes mellitus in terms of incidence [14,15], prevalence [16] and mortality [17]. |
| PubMedID- 20518947 | It is important to mention that the occurrence of prostate cancer in patients with type 2 diabetes is lower than that seen in the general population. |
| PubMedID- 20203524 | Genetic susceptibility to type 2 diabetes is associated with reduced prostate cancer risk. |
| PubMedID- 23251408 | Of course, this should be investigated in future studies, since reduced igf-1 receptor availability in prostate cancer in patients with type 2 diabetes could make them more likely to respond to certain radio- or chemotherapies [23], [24], but might make them resistant to treatments that directly target the igf-1 receptor [24]. |
| PubMedID- 24224094 | The available evidence for the risk of prostate cancer in type 2 diabetes is conflicting. |
| PubMedID- 25684493 | However, it remains unclear whether metformin influences prognosis in prostate cancer (pca) with concurrent type 2 diabetes (t2d). |
| PubMedID- 21148757 | Metformin and the incidence of prostate cancer in patients with type 2 diabetes. |
| PubMedID- 22792092 | Conversely, the mentioned cohort studies reported a lower prevalence of prostate cancer among men with type 2 diabetes compared with that in men without diabetes. |
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