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PedAM

Pediatric Disease Annotations & Medicines




Disease prostate cancer
Phenotype C0001418|adenocarcinoma
Sentences 5
PubMedID- 21134280 In the prostate, akr1c3 is up-regulated in localized and advanced prostate adenocarcinoma, and is associated with prostate cancer (pca) aggressiveness.
PubMedID- 22606612 We emphasize that a suspicion of prostate cancer in men with adenocarcinoma of undetermined origin is important for an adequate diagnostic and therapeutic approach.
PubMedID- 26486598 These trends were confirmed in subgroup analyses by both age and tumour type; black caribbeans and black africans displayed the highest incidence in both those aged less than and greater than 50 and in both adenocarcinoma and ‘other’ types of prostate cancer.fig.
PubMedID- 24885368 Ever using a transgenic adenocarcinoma mouse model of prostate cancer demonstrated that the combined treatment of 5-aza-cdr plus castration significantly prolonged survival and that 5-aza-cdr appeared to delay the onset of androgen-independent disease [9]; however, that animal model did not mimic the course of the clinical disease.
PubMedID- 24005834 To explore this provocative concept, we derived androgen-sensitive and -insensitive prostate epithelial cells persistently infected with human herpesvirus 8 (hhv-8), an oncogenic herpesvirus that has been detected in normal prostate epithelium, prostate adenocarcinoma, and biologic fluids of patients with prostate cancer, to explore its effects on transition to hormone-refractory disease.

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