PedAM
Pediatric Disease Annotations & Medicines
| Disease | progressive multifocal leukoencephalopathy |
| Phenotype | C0409974|lupus erythematosus |
| Sentences | 3 |
| PubMedID- 22687798 | Mefloquine improved progressive multifocal leukoencephalopathy in a patient with systemic lupus erythematosus. |
| PubMedID- 23459383 | In the majority of cases reductions occurred during the first 12 weeks and stabilized within the course.27 serious aes included pathological liver function, neutropenia, and trigeminal neuralgia as well as one case of progressive multifocal leukoencephalopathy in a patient with systemic lupus erythematosus.27 no opportunistic infections and cases of death related to the study drug were reported. |
| PubMedID- 24194647 | The most significant error pertains to a statement made within the safety section, which states: “serious adverse effects (aes) included pathological liver function, neutropenia, and trigeminal neuralgia as well as one case of progressive multifocal leukoencephalopathy (pml) in a patient with systemic lupus erythematosus.” we would like to draw the authors’ attention to the fact that this case of pml pertains to the use of the related drug, leflunomide, and not teriflunomide as suggested. |
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