PedAM
Pediatric Disease Annotations & Medicines
| Disease | primary myelofibrosis |
| Phenotype | C0027022|myeloproliferative disease |
| Sentences | 2 |
| PubMedID- 20801055 | We have studied tgfbeta1 levels in philadelphia-negative (ph-) myeloproliferative diseases, evaluating patients with primary myelofibrosis (pmf) that is characterized by increased numbers of circulating progenitor cells and bone marrow (bm) fibrosis, and patients with polycythemia vera (pv) or essential thrombocythemia (et) that do not present bm fibrosis. |
| PubMedID- 20200965 | (16) pdgf-a has been shown to play a role in the etiology of fibrosis during tissue regeneration and a wide variety of pathologic conditions, including bone marrow fibrosis in patients with myeloproliferative diseases. |
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