PedAM
Pediatric Disease Annotations & Medicines
| Disease | precocious puberty |
| Phenotype | C0020676|hypothyroidism |
| Sentences | 5 |
| PubMedID- 23901203 | The clinical syndrome of severe primary hypothyroidism associated with isosexual precocious puberty in females was first described by kendle in 1905. |
| PubMedID- 23329774 | Van wyk-grumbach syndrome is a rare disease characterized by precocious puberty associated with prolonged hypothyroidism and multicystic enlarged ovaries. |
| PubMedID- 23725039 | The true isosexual precocious puberty that results from prolonged hypothyroidism (the van wyk-grumbach syndrome) is unique among the causes of precocious puberty in that bone age is often delayed at presentation. |
| PubMedID- 24040602 | hypothyroidism with precocious puberty was first described by kendle in 1905 [3]. |
| PubMedID- 24251145 | Van wyk and grumbach first reported multicystic ovaries with precocious puberty in patients with hypothyroidism in 1960. |
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