PedAM
Pediatric Disease Annotations & Medicines
| Disease | portal vein thrombosis |
| Phenotype | C0155773|portal vein thrombosis |
| Sentences | 109 |
| PubMedID- 26357616 | A typical example of prehepatic portal hypertension is extrahepatic portal vein thrombosis, while a purely post-hepatic portal hypertension example is the budd–chiari syndrome (bcs) commonly due to membranous obstruction of the inferior vena cava.3–5 nevertheless, the main cause of biochemical liver abnormalities in patients with connective tissue diseases (ctd) is treatment with potentially hepatotoxic drugs or coexisting viral hepatitis.1 fibrotic autoimmune diseases are characterized pathogenetically by an inflammatory process that induces and sustains robust fibrosis. |
| PubMedID- 26539214 | portal vein thrombosis, present in 2 to 35% of liver recipients, is an unfavorable condition to perform lt; however, nowadays most patients with pvt are amenable to conventional lt [1, 2]. |
| PubMedID- 26309413 | Sex, age, tumor size, and tumor quantity were not statistically significant predictors of postoperative survival times; however, tumor stage, child classification, and portal vein thrombosis were correlated with survival time in these patients (table 2). |
| PubMedID- 24649244 | One case was complicated by portal vein thrombosis following percutaneous transhepatic cholangiodrainage for obstructive jaundice, and in 1 patient, post-operative pathological examination demonstrated an absence of invasive ductal adenocarcinoma. |
| PubMedID- 21674145 | Some studies suggested that the decrease of plasma pc or atiii reflects the development of vod [29, 30], portal vein thrombosis [31], or early occurrence of trcs [18], while others could not verify their roles in the differential diagnosis of trcs [14, 16]. |
| PubMedID- 21769289 | portal vein thrombosis resulted in high portal pressure and increased blood flow in an inferior mesenteric venous-inferior vena cava shunt, and hepatic encephalopathy with hyperammonemia was aggravated. |
| PubMedID- 23322979 | portal vein thrombosis (pvt) is a frequent event in patients with cirrhosis which can be treated with anticoagulants, but there are limited data regarding safety and efficacy of this approach. |
| PubMedID- 23148576 | We describe a case of acute portal vein thrombosis (pvt) in a hepatitis c virus (hcv)-positive elderly patient following administration of indomethacin. |
| PubMedID- 23940769 | Our study showed that the presence or absence of portal vein thrombosis did not influence perfusion, cellularity, and glucose metabolism in advanced hccs. |
| PubMedID- 26378714 | Here, we present a rare case of portal vein thrombosis associated with acute cholecystitis in a 31-year-old man. |
| PubMedID- 25684014 | portal vein thrombosis (pvt) is a common complication of end-stage liver disease with an incidence of 0.6-16% in patients with well-compensated disease, increasing up to 35% in cirrhotic patients with hepatocellular carcinoma.1 as recently as the 1990s, pvt was associated with an increased incidence of complications and a higher mortality rate.2 additionally, blood loss volumes in patients with complete thrombosis were reported to be significantly higher than those in patients without pvt or with partial pvt.3 nevertheless, the presence of pvt is no longer considered an absolute contraindication for liver transplantation, as many improvements have been made in surgical technique and perioperative management.2 in this report, we describe using polytetrafluoroethylene (ptfe) jump graft from the inferior mesenteric vein (imv) for portal inflow in a patient with severe portomesenteric venous thrombosis. |
| PubMedID- 25802795 | The most common prothrombotic factors associated with portal vein thrombosis (pvt) are as follows:myeloproliferative disorders (e.g., polycythemia rubra vera, essential thrombocytosis, and myelofibrosis);antiphospholipid syndrome;anticardiolipin antibody;proteins c and s and antithrombin iii deficiency;factor v leiden deficiency;g20210a prothrombin gene mutation;hyperhomocysteinemia;paroxysmal nocturnal hemoglobinuria.the local factors favoring or precipitating development of portal vein thrombosis can be further divided into 3 categories: conditions characterized by local inflammation with or without a systemic inflammatory response, surgical injury to the portal venous system, and malignancy involving the abdominal organs resulting in tumorous invasion or constriction of the portal venous system [6] as follows:local inflammatory lesions:neonatal omphalitis;diverticulitis;appendicitis;pancreatitis;duodenal ulcer;cholecystitis;tuberculous lymphadenitis;injury to the portal venous system:surgical portocaval shunting;splenectomy;colectomy;gastrectomy;cancer of abdominal organs.it seems that a combination of general and local factors is needed to enable the development of pvt, thus establishing the importance of a thorough investigation of those factors when facing a diagnosis of pvt. |
| PubMedID- 23484577 | Computed tomography revealed portal vein thrombosis, which was found in the setting of clostridium difficile colitis. |
| PubMedID- 24718401 | portal vein thrombosis (pvt) is a complication of decompensated cirrhosis and is more likely to occur during late-stage liver cirrhosis1, with a prevalence of approximately 1 per cent in the general population2. |
| PubMedID- 24936497 | This could exert a beneficial effect on portal vein thrombosis by the inhibition of the vascular endothelial growth factor receptor pathway, which may play a pivotal role in portal vein thrombosis onset and evolution, as well as in hepatocellular carcinoma angiogenesis [8]. |
| PubMedID- 21592404 | portal vein thrombosis was identified in eight patients. |
| PubMedID- 24250337 | A computed tomography (ct) angiography showed splenic and portal vein thrombosis, wall thickening of the colon segments from the level of splenic flexure to the rectum, and increasing density in pericolon adipose tissue. |
| PubMedID- 21415584 | portal vein thrombosis may be the key point of hematogenous spread to other sites.7,10 in our case, it is notable that the hcc was initially a small sized single mass without portal vein thrombosis and metastasized to the left-sided colon one and a half years after tace. |
| PubMedID- 24883123 | Although factors such as the ecog ps, afp concentration, and portal vein thrombosis were significantly related to survival in other studies, the suvs from 18f-fdg pet have several advantages over the other potential biological or imaging markers. |
| PubMedID- 26516439 | portal vein thrombosis resulting from tumor infiltration might have also contributed to the high portal venous pressure and led to more severe bleeding in some cases, but it has no statistically significant difference between survivors and non-survivors in our study. |
| PubMedID- 22319743 | We report here on a case of chylous ascite that was caused by acute pancreatitis with portal vein thrombosis, in which the patient showed an impressive response to conservative therapy with total parenteral nutrition and octerotide. |
| PubMedID- 23093957 | First of all we report three cases of portal vein thrombosis in ibd patients; afterwards, we assess the epidemiology, the clinical course, the diagnosis, and the therapeutic approach of this complication of ibd, performing a systematic review based on the clinical literature. |
| PubMedID- 20046497 | The diagnosis of malignant portal vein thrombosis (pvt) has been based on characteristic ct findings including an expansile vein diameter and relatively strong enhancement or obvious direct invasion by a tumor in the adjacent liver parenchyma (12-14). |
| PubMedID- 24868203 | Unlike general cirrhotic patients with portal vein thrombosis, the original mpv in noncirrhotic patients with portal cavernoma is usually obliterated and replaced by a fibrotic cord. |
| PubMedID- 25894607 | Patients with portal vein thrombosis (pvt) or extrahepatic metastasis were considered to receive radiotherapy (three-dimensional conformal radiotherapy or helical tomotherapy) or systemic chemotherapy in addition to tace [15]. |
| PubMedID- 23423240 | portal vein thrombosis (pvt) is more prevalent in patients with liver cirrhosis and hepatocellular carcinoma (hcc) than the general population.1 benign pvt usually results from portal venous hypertension and venous stasis, whereas malignant pvt is formed by direct invasion of the portal vein by malignant neoplasms, such as hcc.2 several imaging features have been used to differentiate malignant pvt from benign pvt. |
| PubMedID- 25952620 | The therapeutic management of an acute portal vein thrombosis is based on the clinical presentation of the patient and includes systemic anticoagulation as well as local thrombolysis, mechanical thrombectomy, angioplasty, a combination of these or the creation of a transjugular intrahepatic portosystemic stent shunt (tipss) in more symptomatic patients (for more detailed information please refer to the review by lang et al.) |
| PubMedID- 24179551 | portal vein thrombosis (pvt) was present in 13 patients (32.5%). |
| PubMedID- 25700311 | As reported by capussotti et al,5 operative mortality related to liver function or portal pressure (liver failure, portal vein thrombosis, esophageal bleeding) was significantly higher in patients with pht. |
| PubMedID- 25342120 | portal vein thrombosis is frequently observed in patients with liver cirrhosis or hcc. |
| PubMedID- 26208136 | Based on multivariate analysis with the cox proportional hazards model, tumor size and portal vein thrombosis were identified as independent predictors of postoperative survival in hbv-hcc patients. |
| PubMedID- 20103954 | One donor developed portal vein thrombosis which occurred early in the protocol. |
| PubMedID- 26423615 | Peritoneal tuberculosis can present with unusual manifestations like portal vein thrombosis and transudative ascites in the absence of portal hypertension making the diagnosis a dilemma. |
| PubMedID- 26421021 | Thus, portal vein thrombosis is no longer considered to be a contraindication in patients undergoing liver transplantation. |
| PubMedID- 22909075 | We aimed to characterize the pre-transplant portal vein thrombosis in a cohort of liver transplant recipients, and to identify independent risk factors for this complication. |
| PubMedID- 23613103 | Among patients with portal vein thrombosis (pvt) (n = 33), the median ttp and os were 4.5 months (2–7 months) and 5 months (2–8 months), respectively, in patients with td <205 gy and 10 months (6–15.2 months) and 21.5 months (12–28.5 months), respectively, in those with td >205 gy (p = 0.039 and 0.005). |
| PubMedID- 25810714 | Recent evidence suggests the potential relationship of the survival with the occurrence of portal vein thrombosis (pvt) in liver cirrhosis [10]. |
| PubMedID- 21450059 | When portal vein thrombosis occurs in patients with contraindications to anticoagulation, there is a role for initial conservative management without aggressive anticoagulation therapy and such patients must be approached on an individualized basis. |
| PubMedID- 23876309 | Malignant portal vein thrombosis is seen in 44% of cases of hcc[47,48]. |
| PubMedID- 24603710 | There was portal vein thrombosis in 19% of patients at the time of diagnosed. |
| PubMedID- 23760378 | Alcohol related chronic liver disease and portal vein thrombosis) were included in respective aetiology groups. |
| PubMedID- 24489434 | portal vein thrombosis was in one case only (2.5%); portal vein thrombosis was diagnosed by color doppler us; medical treatment in the form of increasing the dose of anticoagulants and changing from oral anticoagulant into injectable form was tried. |
| PubMedID- 23418389 | It is well known that portal vein thrombosis may cause worsening of liver function according to the increase of portal pressure and impaired liver vascularization in a cirrhotic patient [48], which means that the liver function in hcc patients with pvtt tends to deteriorate significantly compared to other patients without liver dysfunction. |
| PubMedID- 26157747 | However, approximately 10-40% patients with hcc have portal vein thrombosis (pvt) at the time of diagnosis.34 overall survival have been reported to be much shorter in patients with pvt, compared to patients without pvt, because these patients have more chances to have metastatic disease at diagnosis and fewer therapeutic options. |
| PubMedID- 24775062 | Contrast enhanced ct also confirmed portal vein thrombosis formation in this patient (figure 2). |
| PubMedID- 23403613 | The hb, hcv, d-dimer and portal vein thrombosis were included in multivariate logistic regression analysis. |
| PubMedID- 25253359 | Spontaneous resolution of portal vein thrombosis in cirrhosis: where do we stand, and where will we go? |
| PubMedID- 20492727 | portal vein thrombosis (pvt) is a common complication in patients with advanced-stage hcc, occurring in 20%-80% of these patients [4-6]. |
| PubMedID- 23826080 | From univariate analysis, the significant prognostic factors were fbx8 expression (p = 0.005), portal vein thrombosis (p<0.001), differentiation (p = 0.001), distant metastasis (p = 0.004), dissemination (p<0.001, table s3 in file s1). |
| PubMedID- 25013632 | Allograft (a) and patients (b) survival of liver transplant recipients with and without portal vein thrombosis who operated in pre-meld and meld era. |