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PedAM

Pediatric Disease Annotations & Medicines




Disease portal hypertension
Phenotype C0014867|esophageal varices
Sentences 35
PubMedID- 26537033 Many of the eggs (about a half) excreted by s. mansoni enter the systemic circulation via the portal vein and lodge in the liver [4], where they give rise to vascular and inflammatory granulomatous changes that can lead to periportal fibrosis, portal hypertension with development of esophageal varices, and the risk of life-threatening hematemesis.
PubMedID- 24633079 Liver cirrhosis and portal hypertension complicated by ruptured gastroesophageal varices may lead to hemorrhagic shock, resulting in events as (i) reduction of blood pressure; (ii) endogenous vasoconstrictors release in an attempt to maintain blood pressure; (iii) vascular hyporeactivity to vasoconstrictors.
PubMedID- 26122248 Adult studies clearly support the use of pharmacologic (beta blockers) and endoscopic (endoscopic band ligation, ebl) management for both primary and secondary prophylaxis of esophageal varices in patients with portal hypertension.
PubMedID- 22764308 In this report, we present a case of isolated liver tuberculosis (tb) as a cause of non-cirrhotic portal hypertension leading to bleeding esophageal varices.
PubMedID- 26011514 Further exclusion criteria were chronic alcohol abuse; chronic liver disease or increase in transaminases more than 3 times above the normal upper range limit; presence of portal hypertension with esophageal varices; known hypersensitivity to ifx or fcm; history of acquired iron overload; myelodysplastic syndrome; pregnancy or lactation; known active infection; clinically significant overt bleeding; active malignancy or chronic renal failure; surgery with relevant blood loss (hb decrease>2g/dl) in the 3 months prior to the study; known human immunodeficiency virus; hepatitis b or hepatitis c virus infection; significant cardiovascular disease.
PubMedID- 24765373 Three patients of portal hypertension with esophageal varices developed repeat episodes of hematemesis.
PubMedID- 22168083 Research objective: studying the features of the collateral venous blood flow and the basic ways of the formation of gastroesophageal varices in patients with cirrhosis and portal hypertension.
PubMedID- 23781362 These patients with chronic portal vein thrombosis must be examined periodically for disease progression, esophageal varices and complications of portal hypertension.
PubMedID- 26333179 Results: twenty two patients (55%) showed positive signs of portal hypertension; 18 with esophageal varices (f0; 1, f1; 8, f2; 9), 2 with gastric varices (f1; 1, f2; 1) and 7 with mild ascites.
PubMedID- 26081479 portal hypertension with ascites and esophageal varices were identified.
PubMedID- 21771955 Conclusion: mr imaging azygos flow measurement appears to be a promising technique for detecting high-risk esophageal varices in patients with portal hypertension.
PubMedID- 24581591 Schistosomiasis, a worldwide spread endemic parasitic disease, may evolve to severe forms of the disease with huge spleen and gastroesophageal varices due to presinusoidal portal hypertension.
PubMedID- 20931432 The purpose of this study was to investigate any correlation between the diameters of esophageal mural veins as observed on routine contrast-enhanced magnetic resonance angiography and the endoscopic grades of esophageal varices in patients with portal hypertension.
PubMedID- 20852922 At the time of presentation, portal hypertension with hepato-splenomegaly and oesophageal varices, as well as grade ii hepatic encephalopathy were diagnosed.
PubMedID- 25481588 portal hypertension which usually leads to bleeding from oesophageal varices in children remain a difficult medical problem.
PubMedID- 20927629 Methods: case 1 was an 11-year-old boy diagnosed with rupture of the esophageal varices and hypersplenism due to congenital extrahepatic portal hypertension.
PubMedID- 26166111 Contrast-enhanced ct showed portal hypertension with esophageal varices, dilated bilateral intrahepatic ducts with an intraductal nodule obstructing the hilar bile duct and cbd, but no tumor thrombus in the portal vein or systemic vein and no obvious mass in the hepatic parenchyma (figure 2a and b).
PubMedID- 23626507 A variety of collateral vascular routes, represented by gastroesophageal varices, occur in patients with portal hypertension.
PubMedID- 22249089 Patients included were for investigations and differential diagnosis of isolated hepatomegaly (28 patients), hepatosplenomegaly (22 patients), cholestasis (16 patients), glycogen storage disease (10 patients), and portal hypertension with esophageal varices (4 patients).
PubMedID- 24078893 Gastric varices are less common than esophageal varices in patients with portal hypertension, occurring in up to 33% of patients [1–3].
PubMedID- 22888334 Oesophageal varices (ov) due to portal hypertension are a major concern in cirrhotic patients because of the risk of bleeding and related high mortality [1].
PubMedID- 21912056 Conclusions: in this study we have validated the use of the platelet count/spleen diameter ratio for the noninvasive diagnosis of esophageal varices in patients with portal hypertension caused by schistosoma infection.
PubMedID- 26158259 Modified sugiura operation for idiopathic portal hypertension with bleeding oesophageal varices.
PubMedID- 23898274 More rarely, oesophageal varices occur in patients with non-cirrhotic portal hypertension that results from thromboses of portal or splanchnic veins.
PubMedID- 22676771 Three patients required discontinuous enteral feeding by nasogastric tube (#7, persistence of severe portal hypertension with oesophageal varices contra-indicated the gastrostomy) or by gastrostomy tube (#’s 3 and 8) after 10 to 12 months of miglustat therapy, and one patient (#4) developed epilepsy at the age of 32 months.
PubMedID- 23846362 Background: our research was conducted to introduce a new, compound surgical method for laparoscopic splenectomy (ls) with preoperative endoscopic variceal ligation (evl) and compare the new method's efficiency with that of hassab's operation in patients with severe esophageal varices due to portal hypertension.
PubMedID- 24584572 15–30 % in childhood/early adolescence, often severe complications (e. g., esophageal varices) due to portal hypertension; if possible transplantation (often combined kidney–liver tx)in early manifesting cases, often better than in arpkd.
PubMedID- 22626689 The timepoint of tee probe insertion varies and is based on the fear of bleeding complications in the setting of portal hypertension with esophageal varices.
PubMedID- 21410046 Shunting and nonshunting procedures for the treatment of esophageal varices in patients with idiopathic portal hypertension.
PubMedID- 25881709 With the progression of the disease development of portal hypertension leads to formation of esophageal varices and ascites.
PubMedID- 25883057 Objectives: data regarding agreement on endoscopic features of oesophageal varices in children with portal hypertension (ph) are scant.
PubMedID- 25958482 Gastroesophageal varices develop in 50% of cirrhotic patients with portal hypertension, but can also develop in other pre- or post-hepatic causes of portal hypertension.
PubMedID- 26120303 Our second case also shows the safety of performing eus in patients with large esophageal varices due to portal hypertension.
PubMedID- 26120300 In 2004 she underwent kidney transplantation for polycystic kidney disease and over the years she developed portal hypertension with esophageal varices in a context of caroli disease.
PubMedID- 23213271 The left gastric vein is the major site of esophageal varices in patients with portal hypertension.

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