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PedAM

Pediatric Disease Annotations & Medicines




Disease polyneuropathy
Phenotype C0011854|type 1 diabetes
Sentences 5
PubMedID- 24893232 The evidence from clinical trials shows that intensive glycemic control reduces prevalence of diabetic sensorimotor polyneuropathy in patients with type 1 diabetes mellitus, but variable outcomes are observed in patients with type 2 diabetes mellitus.
PubMedID- 21909836 Aims/hypothesis: high levels of serum heat shock protein 27 (shsp27) have been associated with distal symmetric polyneuropathy in patients with type 1 diabetes.
PubMedID- 22357183 Heart rate variability and sensorimotor polyneuropathy in type 1 diabetes.
PubMedID- 26093645 Although the later stages of dpn are poorly reversible or irreversible [12], there is evidence that improved glycaemic control can prevent the appearance and worsening of polyneuropathy in patients with type 1 diabetes [13], and although trial evidence is scant, the use of modified footwear and increased vigilance of ulcer formation is universally recommended for the prevention of foot ulcers in patients who have dpn [14].
PubMedID- 26109108 We sought to determine whether long-term near-normoglycaemia maintained from the diagnosis of type 1 diabetes is associated with polyneuropathy and cardiac autonomic dysfunction.

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