PedAM
Pediatric Disease Annotations & Medicines
| Disease | pneumonia |
| Phenotype | C1800706|usual interstitial pneumonia |
| Sentences | 40 |
| PubMedID- 23721656 | Chronic eaa may share radiologic as well as histological features of usual interstitial pneumonia and perhaps il-4 can play a similar role in ipf and chronic eaa. |
| PubMedID- 26013144 | Usual interstitial pneumonia (uip) is the histopathology underlying ipf and is characterized by heterogeneity of disease and accumulation of fibroblast foci and collagen with an emphasis on collagen type i (col1) over type iii (col3) [1, 2], and abnormalities in other matrix molecules including elastin [3]. |
| PubMedID- 22408196 | The pattern of usual interstitial pneumonia (uip) (subpleural reticular abnormality and honeycombing, with or without traction bronchiectasis, in the lung basal regions) on chest hrct in the absence of other known causes for uip is typical, thus emphasising the diagnostic role of imaging. |
| PubMedID- 24468083 | Every patient had typical features of usual interstitial pneumonia on high-resolution ct. all were treated with corticosteroids and cyclophosphamide, which lead to an improvement in twelve cases. |
| PubMedID- 25922588 | Usual interstitial pneumonia (uip) is the most common of the idiopathic interstitial pneumonias (iips).1 uip can be idiopathic (idiopathic pulmonary fibrosis, ipf), may be secondary to certain inhalational exposures and medications, or occur in the context of connective tissue diseases (ctds). |
| PubMedID- 23855653 | All cases had a typical pattern of usual interstitial pneumonia (uip) in chest hrct scan. |
| PubMedID- 26200642 | Patients who have symptomatic chronic obstructive pulmonary disease with severe bulla or emphysema, who have usual interstitial pneumonia with little functional reservoir, or who have de novo lung cancer after previous pulmonary resection are not rare in our routine practice. |
| PubMedID- 25477529 | Of note, usual interstitial pneumonia, characterised as temporally heterogeneous fibrosis, is not seen in infants. |
| PubMedID- 23538739 | We describe a case of progression of usual interstitial pneumonia (uip)/idiopathic pulmonary fibrosis (ipf) during ifnα treatment, which culminated in a fatal acute exacerbation of ipf (ae-ipf). |
| PubMedID- 23703852 | Usual interstitial pneumonia-pattern fibrosis in surgical lung biopsies. |
| PubMedID- 26266064 | Ct scan of the thorax was classified as usual interstitial pneumonia (uip) with reticular infiltrates and honeycombing predominantly in the subpleural areas of the lower lobes, without possibility to differentiate between idiopathic pulmonary fibrosis and fibrosis secondary to vasculitis on radiological grounds (figure 3). |
| PubMedID- 23705860 | Our group has recently shown that patients with a usual interstitial pneumonia (uip) pattern have a poor prognosis in chronic hp [7]. |
| PubMedID- 20727133 | Usual interstitial pneumonia (uip) is rare in children [88]. |
| PubMedID- 23683442 | The 66-year old caucasian female patient suffered from end-stage pulmonary fibrosis caused by usual interstitial pneumonia (uip) first diagnosed in november 2004. according to the guidelines of the international society for heart and lung transplantation, the patient was submitted to double sided lung transplantation in august 2009. immediate post-operative course was complicated by prolonged respiratory weaning with the necessity of percutaneous tracheotomy. |
| PubMedID- 25191493 | Usual interstitial pneumonia was seen in 12.5% and organizing pneumonia in 26.7% of patients. |
| PubMedID- 24473559 | A cox regression analysis showed a high risk of death for the patients with usual interstitial pneumonia and a high percentage of vessel cells immunostained for the angiotensin 2 receptor in the lymphatic vessels. |
| PubMedID- 22882269 | Aims: to evaluate the histological characteristics differentiating chronic hypersensitivity pneumonitis (chronic hp) with a usual interstitial pneumonia (uip)-like pattern from idiopathic pulmonary fibrosis (ipf)/uip. |
| PubMedID- 20929558 | The histological correlate of ipf is usual interstitial pneumonia (uip), in which areas of interstitial fibrosis of various ages are interspersed with normal lung [1,2]. |
| PubMedID- 22628937 | [3] disorders such as sarcoidosis, usual interstitial pneumonia, and cystic fibrosis, which cause severe fibrosis of the upper lobes, may also exert sufficient tracheal traction to result in tracheal enlargement. |
| PubMedID- 21265830 | The classical histopathological pattern of ipf is one of usual interstitial pneumonia characterized by evidence of patchy epithelial damage including type ii pneumocyte hyperplasia, together with abnormal proliferation of mesenchymal cells, varying degrees of fibrosis and overproduction and disorganized deposition of collagen and ecm – this results in significant distortion of pulmonary architecture and honeycombing (figure 1). |
| PubMedID- 20126467 | Subjects were also excluded if they had histologic patterns on lung biopsy (or explant) other than usual interstitial pneumonia (uip) or, in one case, end-stage fibrotic lung disease with honeycombing [51]. |
| PubMedID- 26460792 | Of numerous types of ild, usual interstitial pneumonia (uip) patterns on chest computed tomography (ct) are reported to be associated with the risk for acute exacerbation of ild in several conditions. |
| PubMedID- 24468008 | Diagnosis is made either by pathology consistent with usual interstitial pneumonia or radiographic findings showing areas of fibrosis and honeycombing in the absence of an alternate diagnosis [5]. |
| PubMedID- 22815997 | A diagnosis of usual interstitial pneumonia (uip) was confirmed by a lung pathologist in all ipf cases. |
| PubMedID- 24205507 | Usual interstitial pneumonia (uip) and nonspecific interstitial pneumonia (nsip) are the main patterns of ild described in ra although also other forms, including lymphocytic interstitial pneumonia (lip) and organizing pneumonia (op), have been less commonly observed [14, 31, 32]. |
| PubMedID- 23268535 | The histological correlate of ipf, usual interstitial pneumonia (uip), is characterized by temporally heterogeneous lung architectural distortion and dense collagen and extracellular matrix (ecm) deposition in the interstitium, alveolar collapse, and the presence of fibroblastic foci. |
| PubMedID- 22488224 | Usual interstitial pneumonia (g) showing alternating areas of normal parenchyma (asterisks), honeycombing (triangles) and organizing fibrosis with fibroblastic foci (ff), in detail; anti-d2-40 immunohistochemical stains lymphatics (arrows; h) with a large area or dilated in the peripheral region of honeycombing changes; note fibroblastic foci (ff) overlying the surface of the airspace or enlarged and remodeled airspaces with dense scars in the walls (asterisks). |
| PubMedID- 23107232 | The objective of this study is to assess the accuracy with which histopathologic criteria of usual interstitial pneumonia (uip) can be identified in transbronchial biopsy (tbb) and to assess the usefulness of tbbx in predicting a the diagnosis of uip pattern. |
| PubMedID- 23025845 | The specimens of fibrotic lesions showed usual interstitial pneumonia in histology, characterized by fibroblastic foci and excessive deposition of the ecm (figures1f,2f,3f). |
| PubMedID- 20502709 | A radiographic ct pattern of usual interstitial pneumonia (uip), which is consistent with a diagnosis of ipf, is seen in 74% of cases and a pathologic pattern of uip is seen in 86% of surgical lung biopsies. |
| PubMedID- 26448696 | The french vasculitis study group reported that there were signs of usual interstitial pneumonia (uip) in 6 cases and non-specific interstitial pneumonia in one case, whereas the type of interstitial diffuse pneumonia was unspecified in 5 cases among the 12 patients with aav and pulmonary fibrosis by high-resolution computed tomography (hrct).13 in a retrospective study of 17 patients presenting with pulmonary fibrosis and a positive anca testing by the french pulmonology group, hrct analysis showed honeycombing, reticular intralobular opacities and traction bronchiectasis in all the patients with some degree of ground-glass attenuation (usually limited), whereas air-space consolidation was rare.14 in a french retrospective multicenter study including 49 patients with pulmonary fibrosis associated with aav, 42/49 patients were retrospectively reviewed, and typical uip was the main hrct pattern (n = 18, 43%).15 in a japanese retrospective study of 31 patients with pulmonary fibrosis and mpo-anca, chest hrct scan images showed reticulonodular shadows, honeycombing, and decreased lung volume, all of which were found predominantly in the lower and outer regions of the lung, and the histopathological pattern of pulmonary fibrosis could be classified as a uip pattern in all 11 autopsied cases.9 in another japanese retrospective study of 61 patients with ipf, the initial hrct scans of the 9 mpo-anca-positive patients showed subpleural reticular opacities, traction bronchiectasis, and honeycombing7; however, because these findings were also frequently observed in mpo-anca-negative cases, no differences were found between the 2 groups. |
| PubMedID- 26185436 | On the other hand, histological evaluation at autopsy revealed unexpected dense fibrosis of usual interstitial pneumonia (uip) pattern both in the upper and lower lung areas. |
| PubMedID- 24038004 | Ra-ild on hrct was classified as a usual interstitial pneumonia (uip) pattern or a non-uip pattern according to recent guideline with slight modification.15 briefly, a uip pattern on hrct was characterised by the following: subpleural and basal predominance; reticular abnormalities; honeycombing with or without traction bronchiectasis and the absence of features listed as inconsistent with a uip pattern; including upper or mid-lung predominance, peribronchovascular predominance, extensive ground-glass abnormalities, profuse micronodules, discrete cysts, diffuse mosaic attenuation/air-trapping and consolidation in bronchopulmonary segment(s)/lobe(s). |
| PubMedID- 26137341 | The usual interstitial pneumonia (uip) histopathological pattern is more commonly seen in ra as compared to other connective tissue disorders (ctd) where nonspecific interstitial pneumonia (nsip) is the more prevalent pattern [7]. |
| PubMedID- 26528058 | Usual interstitial pneumonia (uip) is the most common histopathological form of diffuse lung fibrosis occurring in older adults, first described by liebow in 1969 [16]. |
| PubMedID- 22135741 | Six out of 10 patients (60%) had histopathological biopsy proven ipf/usual interstitial pneumonia (uip) whereas in the remaining four diagnosis was based on the radiological uip pattern. |
| PubMedID- 23741087 | [5] symptomatic pulmonary fibrosis with a usual interstitial pneumonia pattern on high resolution computerized tomography and histopathology was seen in our case 2 years after the influenza infection. |
| PubMedID- 26523279 | However, the usual interstitial pneumonia (uip) pattern of lung fibrosis, which is the histologic appearance of the fibrotic pattern of ipf, also occurs in a small number of young people. |
| PubMedID- 24834127 | Usual interstitial pneumonia (uip), the histological presentation of ipf, is marked by patches of fibrotic tissue in areas of normal appearing lung [1]. |
| PubMedID- 23468849 | Idiopathic pulmonary fibrosis (ipf), morphologically usual interstitial pneumonia, is a chronic progressive disease of unknown aetiology with irreversible scarring in the lung [1]. |
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