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PedAM

Pediatric Disease Annotations & Medicines




Disease pneumonia
Phenotype C0085786|idiopathic interstitial pneumonia
Sentences 26
PubMedID- 20502709 We have previously reported that ∼25% of human subjects with the sporadic idiopathic interstitial pneumonias have short telomere lengths (<10th percentile) in the absence of telomerase mutations[19], suggesting a role of this epigenetic modification in the development of non-familial pulmonary fibrosis.
PubMedID- 24082893 Idiopathic pulmonary fibrosis (ipf), the most common form of the idiopathic interstitial pneumonia, is a chronic, progressive, devas-tating, irreversible, and usually lethal human interstitial lung disease of unknown cause that unfortunately leads to death in a short time after diagnosis(12).
PubMedID- 23734820 Idiopathic interstitial pneumonias (iips) make up a heterogeneous group of diseases, which are collectively included in the umbrella term “interstitial lung diseases (ilds)” [1].
PubMedID- 23400027 Our present study is limited by the small number of patients, even though statistically significant differences were found between patients with dermatomyositis and those with idiopathic interstitial pneumonia regarding pulmonary factors (p < 0.01) as shown in table 1. there is a need for larger studies to further examine the parameters affecting exercise capacity in patients with dermatomyositis using methods such as multivariate regression analysis.
PubMedID- 24270907 Theoretically, idiopathic interstitial pneumonias could be caused by theepstein-barr virus, cytomegalovirus, adenovirus, hepatitis c virus, respiratorysyncytial virus, and herpesvirus, which may be present in such small amounts or suchconfiguration that routine histopathological analysis or viral culture techniquescannot detect them.
PubMedID- 24368713 The diffuse idiopathic interstitial pneumonias describe a spectrum of parenchymal lung diseases sharing clinical, physiological, radiological and pathological similarities, including varying degrees of fibrosis, inflammation and vascular injury.1 idiopathic pulmonary fibrosis (ipf) is associated with usual interstitial pneumonia (uip), poor survival and limited treatment options.2 interstitial lung disease (ild), most typically presenting as non-specific interstitial pneumonitis, is a leading cause of death in systemic sclerosis (ssc)3 and a prominent clinical feature of other connective tissue diseases (ctds), including idiopathic inflammatory myopathy (iim) and sjögren syndrome.
PubMedID- 23206520 Here, we report one case of idiopathic interstitial pneumonia (iip) diagnosed by clinic-radiologic-pathological (crp) method, in which uip pattern existed with nsip; the sample was a whole right lung removed from pneumonectomy.
PubMedID- 26202767 Ct images of 74 patients with fibrotic idiopathic interstitial pneumonias (ipf, 36; non-specific interstitial pneumonia, 9; unclassifiable idiopathic interstitial pneumonia, 29) were analyzed via in-house computer software, which automatically calculated haa%, ca%, mean lung density (mld), standard deviation of lung density (sd-ld), kurtosis, and skewness from ct attenuation histograms.
PubMedID- 22205929 These results implicate for the first time the hsv-1 with fibrotic idiopathic interstitial pneumonias since the virus presented similar incidence in two different biological samples.
PubMedID- 23181688 The first generally accepted classification of idiopathic interstitial pneumonia was introduced by liebow in 1975[2].
PubMedID- 24627689 Idiopathic interstitial pneumonia is classified into four categories: usual interstitial pneumonia (uip), desquamative interstitial pneumonia, nonspecific interstitial pneumonia, and acute interstitial pneumonia.1,2 uip, which is clinically known as idiopathic pulmonary fibrosis (ipf), is notorious for its poor prognosis, with a median survival of 2.8 to 5 years.3,4 some studies have suggested an association between uip and lung cancer,4-6 but reliable clinical and histological information regarding lung neoplasms in patients with uip is scarce due to the rarity of the simultaneous occurrence of these conditions.
PubMedID- 26415510 Human lung biopsies of patients with idiopathic interstitial pneumonias (iip), ipf and nsip, and human control lung tissue samples, were obtained in accordance to an approved protocol by the institutional ethics committees of the university hospitals geneva (hug) and the hôpital bichat, paris.
PubMedID- 23984154 Though the ats/ers consensus classification on idiopathic interstitial pneumonias suggest that a diagnosis of cop may be confirmed by transbronchial biopsy in the appropriate clinical setting, many experts believe that a surgical lung biopsy is needed for confirmation as such pathological changes can occur around vasculitis, eosinophilic pneumonia, nonspecific interstitial pneumonia, hypersensitivity pneumonitis, and malignancy [1, 4].
PubMedID- 23209339 It is known to be a marker for diffuse lung disorders, such as idiopathic interstitial pneumonia [6], and serum concentrations of the kl-6 antigen increase in patients with malignant tumors, especially lung, breast, and pancreatic cancer [5], and hepatocellular carcinoma [3].
PubMedID- 21980229 Application of this method of analysis had been done for asbestosis and idiopathic interstitial pneumonia (iip) lung specimens, and the distribution and content of asbestos particles or other particles has been determined in association with the expression of disease-related proteins.
PubMedID- 26013144 It is the most common of the idiopathic interstitial pneumonias, is increasing in prevalence, and it is a progressive disease that causes significant morbidity and mortality.
PubMedID- 24023556 181 patients with fibrotic idiopathic interstitial pneumonia (89% diagnosed as definite/probable ipf) were randomized to receive co-trimoxazole 960 mg twice daily or placebo for 12 months in addition to usual care.
PubMedID- 25378843 [45] with subsequent characterization of idiopathic interstitial pneumonias (iips),[16] an increase in the burden of ipf is being reported from various centers in india.
PubMedID- 25837172 Although ctd-ild is known to be associated with a more favorable prognosis than idiopathic interstitial pneumonia of equivalent severity,4,5 there are few publications that found significantly better pft results in both the ctd-ild or uctd-ild groups at diagnosis or during the clinical course.12,24 in this study, a significant number of patients who had positive serological results on the fana and anca tests were included.
PubMedID- 26056507 Ild of unknown etiology is referred to as idiopathic interstitial pneumonia (iip), which is sporadic in the majority of cases.
PubMedID- 26557259 Ipf is the most common of the idiopathic interstitial pneumonias and is a chronic fibrotic, irreversibly progressive ild with an estimated incidence in the nordic countries of 0.4–10/100,000 corresponding to 1–980 new ipf patients each year in iceland and sweden, respectively.
PubMedID- 23316404 The idiopathic interstitial pneumonias (iip) is defined as a group of chronic, progressive diffuse parenchymal lung diseases with unclear cause, characterized by expansion of the interstitial compartment of inflammatory cells, and is potential to develop pulmonary fibrosis in many cases.
PubMedID- 24578677 Idiopathic ppfe has been listed as one of the rare idiopathic interstitial pneumonias (iips) in the revised international multidisciplinary classification of the iips [2].
PubMedID- 26566367 Twenty-two patients with ae-idiopathic interstitial pneumonia (16 patients with ipf and six patients with nsip) were enrolled in our study.
PubMedID- 26029526 The recent published updated classification of idiopathic interstitial pneumonias (iip) classifies ippfe in the group of rare iip [4].
PubMedID- 21687544 She had sudden onset and rapid progression of her symptoms, which helped to differentiate aip from other forms of idiopathic interstitial pneumonia in which duration of symptoms is usually in months to years [3, 14].

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