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PedAM

Pediatric Disease Annotations & Medicines




Disease pneumonia
Phenotype C0010674|cystic fibrosis
Sentences 13
PubMedID- 26175724 It is associated with a number of clinical syndromes, such as endocarditis, urinary infections, and respiratory infections, including pneumonia in patients with cystic fibrosis and the immunocompromised (falagas et al., 2009; looney et al., 2009).
PubMedID- 21402887 Indeed, persistent lung inflammation associated with cystic fibrosis (cf) has been proposed to result, in part, from the failure of alveolar macrophages expressing mutant cftr to correctly acidify their degradative compartments, causing an inability to resolve infection (di et al., 2006; deriy et al., 2009).
PubMedID- 20028803 Pseudomonas aeruginosa is an opportunistic pathogen that causes life-long pneumonia in individuals with cystic fibrosis (cf).
PubMedID- 23272096 Burn wound infections, pneumonia, infections in patients with cystic fibrosis, intra-abdominal infections, chronic ulcers, and sepsis [6].
PubMedID- 25301526 The role of streptococcus pneumoniae in cystic fibrosis (cf) is poorly understood.
PubMedID- 22919633 Non-typeable haemophilus influenzae (nthi) is a gram-negative nasopharyngeal commensal microorganism, and opportunistic pathogen that can mediate human airway diseases such as otitis media (om), acute sinusitis, chronic bronchitis, pneumonia, and exacerbations in patients with cystic fibrosis and chronic obstructive pulmonary disease (klein, 1997; st geme, 2000; sethi and murphy, 2001; murphy, 2003; roman et al., 2004).
PubMedID- 22330747 Caveolin 2, which localizes to the golgi complex but redistributes to plasma membrane, caveolae and rafts when co-expressed with caveolin 1, is a potential key molecule related to the pseudomonas infection causing pneumonia in patients with cystic fibrosis and other immunocompromising conditions [79,80].
PubMedID- 22322268 Background: experience with intravenous and aerosolized forms of colistin for the treatment of ventilator-associated pneumonia (vap) in patients without cystic fibrosis is limited.
PubMedID- 26049740 pneumoniae) carriage rates in patients with cystic fibrosis (cf).
PubMedID- 24832699 We describe a further case of pneumonia in a patient with cystic fibrosis, and outline potential transmission of the organism from healthy family members to this patient.
PubMedID- 24968502 cystic fibrosis presenting with persistent pneumonia --a case study of a 3-month-old adopted baby.
PubMedID- 24659602 Chronic pseudomonas aeruginosa infections are the main cause of morbidity among patients with cystic fibrosis (cf) due to persistent lung inflammation caused by interaction between this bacterium and the immune system.
PubMedID- 26515683 cystic fibrosis, also hallmarked with pulmonary inflammation, is caused by mutations in cftr, the expression of which is temperature-sensitive.

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