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PedAM

Pediatric Disease Annotations & Medicines




Disease pneumoconiosis
Phenotype C0021053|immune disease
Sentences 1
PubMedID- 26056507 In addition, silica exposure may also lead to the development of various autoimmune diseases.117 ra with pneumoconiosis following silica exposure is called caplan’s syndrome.118 results from genetic association studies on pneumoconiosis indicate that the hla-b54 allele is associated with silicosis in japanese patients.119 because drb1*04:05 is the dominant se allele in the japanese ra population, the hla-b*54:01-drb1*04:05 haplotype underlies the susceptibility of this ethnic group to caplan’s syndrome.

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