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PedAM

Pediatric Disease Annotations & Medicines




Disease pituitary adenoma
Phenotype C0027662|multiple endocrine neoplasia
Sentences 3
PubMedID- 22584716 (11) reported the first case of a pituitary adenoma associated with multiple endocrine neoplasia type 1 (men1) that was treated with temozolomide.
PubMedID- 22091429 pituitary adenoma is commonly associated with multiple endocrine neoplasia type 1 (men 1), however is not associated with men-2a.
PubMedID- 23470560 Interestingly, p27kip1 was shown to be predictive for dual pi3k-mtor inhibitor sensitivity in a cell-based model of pituitary adenomas from rats with multiple endocrine neoplasia-like syndrom [21] and p27kip1 expression correlated with rapalog sensitivity in the nci-60 cell line platform [45].

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