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PedAM

Pediatric Disease Annotations & Medicines




Disease pharyngitis
Phenotype C0021345|mononucleosis
Sentences 3
PubMedID- 21448390 Infectious mononucleosis (im), a syndrome of painful lymphodenopathy, sore throat and fatigue, and nasopharyngeal carcinoma (npc), a tumor of epidermoid origin, are strongly associated with epstein-barr virus (ebv), since the ebv genome has been found consistently in the specimens of both disorders.1 however, the precise mechanism(s) by which ebv alters the host immune response and leads to the development of ebv-associated infections and/or malignancies remains to be further elucidated.
PubMedID- 26064752 The most common clinical feature seen in adults and adolescents with infectious mononucleosis is a triad of fever, sore throat, and lymphadenopathy.
PubMedID- 22818256 In order to have uniform medical criteria, we considered as a case of mononucleosis all patients with fever, pharyngitis, and/or lymphadenopathy with positive serology of infection by epstein-barr virus which was considered as confirmation of the diagnosis when at least one of the following markers: viral capsid antigen immunoglobulin m (vca igm), viral capsid antigen immunoglobulin g (vca igg), anti early antigen (anti-ea) is positive.

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