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PedAM

Pediatric Disease Annotations & Medicines




Disease pemphigus vulgaris
Phenotype C0021053|immune disease
Sentences 1
PubMedID- 24646797 The most common autoimmune diseases of the desmosome, pemphigus vulgaris and pemphigus foliaceus (pv and pf), are caused by autoantibodies that bind desmoglein 3 and/or desmoglein 1, resulting in depletion of desmoglein from the desmosome and loss of intercellular adhesion.

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