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PedAM

Pediatric Disease Annotations & Medicines




Disease papilloma
Phenotype C0042769|virus infection
Sentences 2
PubMedID- 23984212 Although considered a benign lesion ip's growth pattern and ability to malignant transformation require extensive primary resection and meticulous follow-up.5,11 its etiology remains unclear although association between virus infection particularly with human papilloma viruses has been proposed, whereas llorente et al12 did not detect genetic material of neither epstein-barr virus (ebv) nor human papillomavirus (hpv) in their series through in situ hybridization and polymerase chain reaction.
PubMedID- 25992219 There was an observed higher incidence of virus infection with human papilloma virus and epstein barr virus in potentially malignant than in malignant lesions; approximately 29% in leukoplakias and lichen planus from sweden, 40% of the toombak users in sudan, and particularly high yields (91%) of hpv dna in oral submucous fibrosis from india.the author concluded that the study data do not at first sight support the conclusion that viruses and tobacco use jointly interact with cell mechanisms in the development of oral cancer.

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