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PedAM

Pediatric Disease Annotations & Medicines




Disease panuveitis
Phenotype C0008526|choroiditis
Sentences 8
PubMedID- 24707270 The prognosis may be difficult to determine due to the overlying similarities of mewds, multifocal choroiditis with panuveitis, punctate inner choroidopathy and azoor, all of which can involve white dots and/or an enlarged blind spot [8, 9].
PubMedID- 22927733 Uveitis-associated choroidal new vessel membranes (ie, choroidal neovascularization [cnv]) are relatively rare complications of posterior segment inflammation,1–10 which mainly occur in multifocal choroiditis with panuveitis (39%), punctate inner choroidopathy (29%), serpiginous choroiditis (18%), and vogt–koyanagi–harada (10%).1–24 the current standard of care involves control of uveitis in a stepladder fashion with oral, periocular, or intraocular corticosteroids, along with immunosuppressive therapies.11,12 when this medical therapy fails to cause cnv regression, additional interventions have been advocated, eg, argon laser photocoagulation, photodynamic therapy, and antivascular endothelial growth factor (anti-vegf) drugs.1–24 the authors’ study group has reported short-term (3 months), mid-term (6 months to 2 years), and 3-year results of intravitreal bevacizumab in inflammatory cnv, showing significant visual improvement and regression of ocular neovascularization in a wide variety of ocular diseases.10–12 the majority of studies analyzing the clinical efficacy of vegf antagonists in uveitis or age-related macular degeneration or myopic cnv are short term (2 years or less).1–24 in the current study, the 5-year visual and anatomic outcomes of intravitreal bevacizumab in inflammatory neovascular disorders in a multicenter, retrospective, consecutive, nonrandomized, interventional study are analyzed.
PubMedID- 21357402 Punctate inner choroidopathy and multifocal choroiditis with panuveitis share haplotypic associations with il10 and tnf loci.
PubMedID- 26286265 Of the 35 clinical trials that used a composite outcome measure, 28 included multiple categories of uveitis, whereas 7 were disorder-specific (5 involving behcet disease; one involving intermediate uveitis; and one involving multifocal choroiditis with panuveitis syndrome).
PubMedID- 22615694 Other wds include multifocal choroiditis with panuveitis, multiple evanescent wds, acute multifocal posterior placoid pigment epitheliopathy, and birdshot chorioretinopathy.
PubMedID- 25390811 Bilateral granulomatous panuveitis with multifocal choroiditis was present.
PubMedID- 24678412 The characteristic inflammatory changes of the choroid and retina are typically yellow-white foci beneath or in the deep retina and include birdshot chorioretinopathy (bcr), acute posterior multifocal placoid pigment epitheliopathy (apmppe), multiple evanescent white dot syndrome (mewds), multifocal choroiditis with panuveitis (mfc), punctate inner choroidopathy (pic), and acute zonal occult outer retinopathy (azoor).
PubMedID- 24876985 It can evolve into panuveitis, with multifocal choroiditis, usually bilateral.

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