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PedAM

Pediatric Disease Annotations & Medicines




Disease pancytopenia
Phenotype C0020541|portal hypertension
Sentences 2
PubMedID- 25956701 Extra-renal cystine accumulation caused multiple endocrinopathies (including adrenal insufficiency, hypothyroidism and primary hypogonadism), neurological symptoms, pancytopenia owing to splenomegaly and portal hypertension due to nodular regenerative hyperplasia, aggravated by splenic vein thrombosis and partial portal vein thrombosis.
PubMedID- 24255608 It is noteworthy that pancytopenia in portal hypertension due toschistosomiasis is caused by intra-splenic blood stasis related to difficult venousdrainage to the liver.

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