PedAM
Pediatric Disease Annotations & Medicines
| Disease | pancreatitis |
| Phenotype | C0011847|diabetes |
| Sentences | 53 |
| PubMedID- 23269874 | Background: recent studies have demonstrated an increased incidence of pancreatitis in patients with type 2 diabetes compared with obese nondiabetic individuals. |
| PubMedID- 24251162 | diabetes due to recurrent pancreatitis secondary to hypercalcemia due to primary hyperparathyroidism. |
| PubMedID- 20412332 | Recent case reports of acute pancreatitis in patients with type 2 diabetes (t2dm) treated with incretin-based therapies have triggered interest regarding the possibility of a mechanism-based association between pancreatitis and glucagon-like peptide-1 mimetics or dipeptidyl peptidase-4 (dpp-4) inhibitors. |
| PubMedID- 24674587 | Prophylactic effects of the glucagon-like peptide-1 analog liraglutide on hyperglycemia in a rat model of type 2 diabetes mellitus associated with chronic pancreatitis and obesity. |
| PubMedID- 19894028 | In one such study, the incidence of pancreatitis was increased in patients with type 2 diabetes treated with the glp-1 analogue liraglutide [10]. |
| PubMedID- 23300896 | Background: increased risks of acute pancreatitis in patients with type 2 diabetes mellitus have been reported recently in several countries. |
| PubMedID- 22410797 | Another patient developed necrotizing pancreatitis with transient diabetes mellitus 10 years after first presentation, for which a partial pancreatectomy was performed. |
| PubMedID- 26512613 | To investigate the effects of dipeptidyl peptidase-4 (dpp-4) inhibitors on the risk of acute pancreatitis in patients with type 2 diabetes.this nationwide population-based cohort study used the diabetes patients dataset of taiwan's national health research insurance research database. |
| PubMedID- 25918533 | If pancreatic autoantibodies are negative, patients have secondary diabetes due to pancreatitis or type 2 diabetes complicated by acute pancreatitis. |
| PubMedID- 22416857 | In addition, the investigators observed an increased risk of acute pancreatitis in patients with diabetes compared with those without diabetes. |
| PubMedID- 22923278 | Aim: to determine oxidant stress and antioxidant capacity in chronic pancreatitis (cp) patients with and without diabetes mellitus. |
| PubMedID- 20371755 | Objective: to review the possible association between glucagon-like peptide-1 (glp-1) agonist use and pancreatitis in patients with type 2 diabetes mellitus. |
| PubMedID- 22687379 | Background: the co-existence of diabetes mellitus (dm) in patients with acute pancreatitis (ap) is linked to poor outcomes. |
| PubMedID- 20682680 | Figure 1 shows the kaplan-meier curve of time to acute pancreatitis in patients with diabetes compared with that in nondiabetic control patients. |
| PubMedID- 20217037 | Aims/hypothesis: diabetes frequently develops in patients with chronic pancreatitis (cp). |
| PubMedID- 21781351 | For further description see table 1. patients having diabetes as a consequence of known chronic pancreatitis, haemochromatosis, mutations in the insulin receptor, lipodystrophy, maturity-onset diabetes of the young, maternally inherited diabetes and deafness, family history of first-degree relatives with type 1 diabetes, insulin requirement within the first year after diabetes diagnosis or a fasting serum c-peptide level ≤ 150 pmol/l at time of recruitment were excluded from the category of clinically defined t2dm. |
| PubMedID- 19703814 | Objective: to report acute pancreatitis in a patient with non-insulin-dependent diabetes mellitus (niddm) receiving exenatide and critically review previous reports. |
| PubMedID- 22230860 | We are reporting a case of dengue hemorrhagic fever complicated by acute pancreatitis in a patient with history of diabetes mellitus type 1 and end stage renal disease on hemodialysis. |
| PubMedID- 21577242 | Objectives: the objective of this study was to assess the risk of acute pancreatitis among patients with type 2 diabetes mellitus (dm) and identify the roles of co-morbidities and anti-diabetic drugs. |
| PubMedID- 24711951 | We report a case of a patient who clinically presented with acute manifested diabetes mellitus associated with isolated granulomatous pancreatitis discovered in the postmortem examination and we present a review of the available literature. |
| PubMedID- 21525466 | Up-to-date observational reports and clinical study data revealed that 44 cases of acute pancreatitis occurred in patients with type 2 diabetes while taking exenatide (8 cases during clinical development and 36 postmarketing reports), 4 cases of pancreatitis in liraglutide-treated patients (in clinical trials), and none during therapy with albiglutide or taspoglutide (51). |
| PubMedID- 23139373 | A recent observational study found a threefold increased risk of pancreatitis in patients with type 2 diabetes (14), making any assessment of causality difficult in this relatively small study. |
| PubMedID- 26125315 | There is increasing evidence suggesting an increased risk for (pancreatic) cancer and pancreatitis in patients with diabetes mellitus. |
| PubMedID- 20103558 | Notably, analysis of pancreatitis in subjects with type 2 diabetes suggests that their risk is increased threefold over nondiabetic subjects (21). |
| PubMedID- 24859164 | Acute pancreatitis in patients with type 2 diabetes mellitus treated with dipeptidyl peptidase-4 inhibitors: a population-based nested case-control study. |
| PubMedID- 23882053 | Other studies have examined lipase and amylase activities in serum (20) and the incidence of acute pancreatitis in patients with type 2 diabetes while receiving different forms of antidiabetes treatment (21–26). |
| PubMedID- 21822421 | diabetes mellitus associated with autoimmune pancreatitis can be treated by steroids, and it can even be cured if the autoimmune attack can be stopped [50, 51]. |
| PubMedID- 24736555 | Incretin treatment and risk of pancreatitis in patients with type 2 diabetes mellitus: systematic review and meta-analysis of randomised and non-randomised studies. |
| PubMedID- 23126518 | Case presentation: we report a case of a 20 year old ugandan female patient who presented with features of chronic tropical calcific pancreatitis complicated by diabetes mellitus, oedematous malnutrition and micronutrient deficiencies. |
| PubMedID- 21180276 | Of all the 12 patients with ipmn, 9 (75.0%) had experienced some symptoms of epigastric discomfort and/or pain as well as backache; 7 cases were with medical history of acute pancreatitis, 5 cases with diabetes, 4 cases with elevated ca19-9, and 2 cases with steatorrhea. |
| PubMedID- 24217090 | There is increasing concern about the development of pancreatitis in patients with diabetes mellitus who received long-term glucagon-like peptide-1 (glp-1) analog treatment. |
| PubMedID- 25401425 | diabetes increases pancreatitis induced systemic inflammation but has little effect on inflammation and cell death in the lung. |
| PubMedID- 20182396 | Among true pancreatic diabetes with chronic pancreatitis, alcoholic pancreatitis was found in the largest sector. |
| PubMedID- 20833867 | The results of this study confirm the excess risk of acute pancreatitis associated with type 2 diabetes previously reported in other observational studies (2,4,5). |
| PubMedID- 25528851 | The severity of chronic pancreatitis with concomitant diabetes was deeper than in the patients without endocrine failure: respectively, the average severity (s) prevailed in 72.7% of patients vs 25%, the cases of expressed and severe severity appeared. |
| PubMedID- 24571389 | In order to find a more reliable biomarker or biomarker panel,several pancreatic cancer related disease states (diabetes, cysticneoplasms of the pancreas, chronic pancreatitis, and obstructive jaundice)along with healthy controls were compared with pancreatic cancer patients.lectin extraction and quantitative proteomics methods were appliedto discover potential serum glycoprotein biomarkers that distinguishpancreatic cancer from the other groups. |
| PubMedID- 22588243 | The following clinical data were extracted from patient case records: age, gender, diabetes mellitus, history of chronic pancreatitis, autoimmune disease, smoking, alcohol consumption, jaundice, weight loss, and pain. |
| PubMedID- 20375642 | Serum hbsag and anti-hcv were examined, and data on smoking, alcohol intake, diabetes, and the history of chronic pancreatitis (cp) were collected. |
| PubMedID- 21701614 | Given the baseline rate of pancreatitis in people with diabetes, it is currently difficult to know if reports of pancreatitis in people on incretin therapies are truly attributable to drug usage. |
| PubMedID- 21324812 | Conclusions: although incretin-based therapy effectively treats type 2 diabetes mellitus, emerging reports of acute pancreatitis in patients receiving sitagliptin and exenatide have prompted the us food and drug administration to issue an alert on these drugs. |
| PubMedID- 21175494 | A 63-year-old woman was admitted for endoscopic treatment of acute on chronic pancreatitis with diabetes and epigastric pain with liver dysfunction due to a large impacted stone within the distal main pancreatic duct. |
| PubMedID- 24764569 | As incretin based drugs are typically second to third line drugs2 and the risk of acute pancreatitis increases with type 2 diabetes and possibly with duration of disease,404142 it is imperative that they are compared with drugs used at the same or a similar stage of diabetes, otherwise this would introduce a time lag bias.43 it is for this reason that our primary comparator group consisted of sulfonylurea users, which we believe is the clinically most appropriate comparator. |
| PubMedID- 21437074 | This is difficult to establish because there is a generalized increased risk of acute pancreatitis in patients with diabetes, obesity or hyperlipemia. |
| PubMedID- 23700194 | [28] reported a higher rate of hospitalizations for acute pancreatitis in patients with type 2 diabetes associated with the use of incretin-based therapies (sitagliptin or exenatide). |
| PubMedID- 20096519 | [complete resolution of insulin-dependent diabetes mellitus in a patient with autoimmune pancreatitis following treatment with corticosteroids]. |
| PubMedID- 24651798 | That study used a large insurance database of more than 1 million people, and reported increased odds of hospitalizations for acute pancreatitis in patients with type 2 diabetes 64 years of age or younger that were prescribed either exenatide or saxagliptin. |
| PubMedID- 24661305 | Incidence and precipitants of hospitalization for pancreatitis in people with diabetes: the fremantle diabetes study. |
| PubMedID- 23576884 | A long-term safety and efficacy study evaluated linagliptin therapy in over 2000patients for a total of 102 weeks and found an overall incidence of 0.2%.19 however, recent discussions have noted thatthe prevalence of pancreatitis among patients with type 2 diabetes is similar to that seenwith incretin hormones. |
| PubMedID- 23522174 | pancreatitis can lead to development of diabetes mellitus, which may be transient (diabetic remission) or permanent through destruction and loss of beta cells. |
| PubMedID- 21994885 | Weight loss or new-onset diabetes mellitus due to pancreatitis is another potential symptom. |
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