PedAM
Pediatric Disease Annotations & Medicines
| Disease | pancreatic cancer |
| Phenotype | C0149521|chronic pancreatitis |
| Sentences | 29 |
| PubMedID- 20510834 | pancreatic cancer in chronic pancreatitis; aetiology, incidence, and early detection. |
| PubMedID- 25848351 | A prediction rule was developed to stratify the risk for pancreatic cancer in patients with chronic pancreatitis, where gender, mass location, mass number, direct bilirubin, and ca 19-9 were included in the calculation [10]. |
| PubMedID- 23018013 | The association of chronic pancreatitis with pancreatic cancer requires strict follow-up, especially in patients with inflammatory masses in the context of chronic pancreatitis. |
| PubMedID- 22057290 | Chronic infection and subsequent inflammation are considered critical environmental and epigenetic factors contributing to tumor progression1, 2. primary examples are gastric cancer and helicobacter pylori infections, hepatocellular carcinoma and viral hepatitis, colitis-associated cancer, and pancreatic cancer associated with chronic pancreatitis1. |
| PubMedID- 21114434 | Conclusions: the prediction rule can provide available risk stratification for pancreatic cancer in chronic pancreatitis patients with focal mass lesions with prior negative eus-fna cytology. |
| PubMedID- 21661440 | Incidence of and risk factors for developing pancreatic cancer in patients with chronic pancreatitis. |
| PubMedID- 21510309 | This study aimed to identify a high risk group for developing pancreatic cancer associated with chronic pancreatitis, particularly the presence of k-ras mutations in the pancreatic juice. |
| PubMedID- 23296709 | We also demonstrated upregulation of duox expression in vivo in pancreatic cancer xenografts and in patients with chronic pancreatitis. |
| PubMedID- 22617158 | Research findings pointing to this direction include the documented relationship of pancreatic cancer risk with chronic pancreatitis (raimondi et al, 2010), as well as with smoking (lynch et al, 2009; vrieling et al, 2010), pre-existing and long-standing diabetes mellitus (huxley et al, 2005), and excess weight (genkinger et al, 2010), all of which are known or suggestive determinants of low-grade inflammatory states (whitcomb, 2004; kolb and mandrup-poulsen, 2005; hotamisligil, 2006; goncalves et al, 2011). |
| PubMedID- 23476808 | Also risk of pancreatic cancer in chronic pancreatitis was dramatically increased with coexistence of diabetes (hr = 33.52), even though the role of dm may be overlooked in the presence of more acknowledged risk factors [116]. |
| PubMedID- 24660091 | Smoking compounds can worsen chronic pancreatitis leading to pancreatic cancer [53]. |
| PubMedID- 23060806 | Using retrospective, histological examination of pancreases resected on suspicion of pancreatic cancer from patients with mass-forming chronic pancreatitis, american and european pathologists have described another unique histological pattern, called idiopathic duct-centric pancreatitis (idcp) (notohara et al., 2003), or aip with granulocytic epithelial lesion (gel) (zamboni et al., 2004). |
| PubMedID- 22973234 | Of particular relevance in this regard were the known increased risk of pancreatic cancer in patients with chronic pancreatitis (raimondi et al., 2010) and the commonalities in gene expression between the stromal compartments of chronic pancreatitis and pancreatic cancer (binkley et al., 2004). |
| PubMedID- 25937765 | pancreatic cancer in chronic pancreatitis. |
| PubMedID- 23384807 | This disruption can result from widespread pancreatic necrosis in acute pancreatitis, fibrotic replacement of the parenchyma as seen in chronic pancreatitis and in patients with pancreatic cancer where normal tissue is replaced by tumour and/or the pancreatic duct becomes obstructed. |
| PubMedID- 22414467 | Among six genes, p16 was more specifically methylated in pancreatic cancer compared with chronic pancreatitis (p=0.016). |
| PubMedID- 22511932 | Given the fact that not all cases of pancreatic cancer are associated with chronic pancreatitis, it could be that other forms of inflammation have a similar effect. |
| PubMedID- 24474940 | Of the patients who progress to chronic pancreatitis, the risk of developing pancreatic cancer by age 70 years is approximately 40%. |
| PubMedID- 24708788 | Mif expression was significantly increased in pancreatic cancer tissues compared with chronic pancreatitis or normal pancreas specimens. |
| PubMedID- 20065943 | Little is known about the mechanism by which cigarette smoke or snus increase the risk of pancreatic cancer in individuals with chronic pancreatitis. |
| PubMedID- 19854016 | For eus, its diagnostic value decreased in differentiating pancreatic cancer for patients with chronic pancreatitis. |
| PubMedID- 22989892 | The aim of this study was to confirm the high incidence of pancreatic cancer in patients with chronic pancreatitis in japan and to determine the factors associated with the risk for pancreatic cancer in patients with chronic pancreatitis. |
| PubMedID- 20103562 | Of perhaps greatest concern in the case of the glp-1–based drugs, including glp-1 agonists and dipeptidyl peptidase-4 (dpp-4) inhibitors, is preliminary evidence to suggest the potential risks of asymptomatic chronic pancreatitis and, with time, pancreatic cancer. |
| PubMedID- 25942306 | pancreatic cancer in patients with recently diagnosed chronic pancreatitis. |
| PubMedID- 23531764 | (2010) used transcript profiling to identify markers to differentiate psc associated with chronic pancreatitis against those of pancreatic cancer, with the ultimate aim of subtyping psc into either inflammation- or tumor-associated-psc. |
| PubMedID- 22022519 | More recently, erkan et al [37] used transcript profiling to identify markers to differentiate pasc’s associated with chronic pancreatitis versus those of pancreatic cancer, with the aim of subtyping pasc's into either inflammation or cancer-associated. |
| PubMedID- 23401773 | Data were confirmed by high-density protein microarray in a large cohort of 140 patients affected by pancreatic cancer, 10 patients with chronic pancreatitis and 87 healthy controls. |
| PubMedID- 23053420 | Gallstones, a cholecystectomy, chronic pancreatitis, and the risk of subsequent pancreatic cancer in diabetic patients: a population-based cohort study. |
| PubMedID- 25789097 | chronic pancreatitis increases the risk of developing pancreatic cancer. |
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