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PedAM

Pediatric Disease Annotations & Medicines




Disease pancreatic cancer
Phenotype C0031269|peutz-jeghers syndrome
Sentences 3
PubMedID- 21189378 Mtor inhibitor treatment of pancreatic cancer in a patient with peutz-jeghers syndrome.
PubMedID- 21512581 We have recently seen a peutz-jeghers syndrome patient with pancreatic cancer whose tumor showed complete loss of lkb1, an inhibitor of mtor.
PubMedID- 25714017 [49] a case reported by klumpen at al successfully used the mtor inhibitor everolimus in a peutz-jeghers syndrome patient with pancreatic cancer to obtain a partial response without additional cytotoxic chemotherapy (table 4).

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