PedAM

Pediatric Disease Annotations & Medicines

Disease	pancreatic cancer
Phenotype	C0028754\|obesity
Sentences	11
PubMedID- 21989024	Objectives: obesity is associated with increased pancreatic cancer risk, although the mechanisms have yet to be detailed.
PubMedID- 24657938	Given that the liver and pancreas have similar embryological origins, it is also plausible, as suggested for nafld, that obesity may lead to pancreatic cancer through pancreatic steatosis [4], [5].
PubMedID- 25017247	Conclusion: the findings suggest that obesity is independently associated with increased pancreatic cancer mortality in african americans.
PubMedID- PMC4070603	Our study adds further evidence to a positive link between visceral abdominal obesity and risk of pancreatic cancer.
PubMedID- 26460214	Premorbid obesity and mortality in patients with pancreatic cancer: a systematic review and meta-analysis.
PubMedID- 20859700	Conclusion: these data show that diet-induced obesity accelerates the growth of murine pancreatic cancer.
PubMedID- 19844672	A possible underlying mechanism to account for an increased risk of pancreatic cancer in people with obesity and/or diabetes is chronically increased pancreatic duct cell replication.
PubMedID- 26472921	This is provocative since pancreatic cancer has been associated with both obesity and type 2 diabetes [48–51].
PubMedID- 22456038	It remains unclear if there is a direct association between obesity and the risk of pancreatic cancer or if it is reflecting other risk factors such as diet and physical inactivity.
PubMedID- 24136929	Genetic factors that modify the associations of obesity and diabetes with pancreatic cancer have previously not been examined at the genome-wide level.
PubMedID- 23029396	Epidemiological studies have suggested that increased risks of pancreatic cancer are associated with tobacco, obesity and high consumption of fat, fish, pork or beef, and that decreased risks are associated with consumption of cruciferous vegetables.

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