PedAM
Pediatric Disease Annotations & Medicines
| Disease | pancreatic cancer |
| Phenotype | C0006625|cachexia |
| Sentences | 13 |
| PubMedID- 22721276 | The skeletal muscle mass appears to be significantly involved in the process of cancer cachexia in patients with pancreatic cancer, being the potential target of various tumor products which can activate protein degradation [17]. |
| PubMedID- 24648112 | pancreatic cancer-induced cachexia is jak2-dependent in mice. |
| PubMedID- 23051772 | Increased gamma-aminobutyrate (gaba, p < 0.01) levels were specific to cachexia in patients with pancreatic cancer. |
| PubMedID- 24624094 | Found that pancreatic cancer patients with cachexia had elevated crp levels and stimulated il-6 production (moses et al., 2009). |
| PubMedID- 23180446 | Increased γ-aminobutyrate (gaba) levels were specific to cachexia in patients with pancreatic cancer. |
| PubMedID- 20590907 | cachexia in pancreatic cancer: new treatment options and measures of success. |
| PubMedID- 25341901 | The highest rate of cachexia was 34.0%(89/262) in patients with pancreatic cancer followed by gastric cancer 22.4%(261/1164), colon cancer 21.7%(146/672), and rectal cancer 20.1%(117/581). |
| PubMedID- 22473907 | Crp was incorporated into a three-factor model of cachexia for patients with pancreatic cancer (fearon et al, 2006). |
| PubMedID- 26136412 | In one of very few similar studies, schmitt et al.24 examined protein levels and phosphorylation status of muscle atrophy/hypertrophy pathway components in eight pancreatic cancer patients with cachexia compared with eight weight-stable cancer or pancreatitis patients.24 they observed reduced levels of akt, myhc, and foxo1 in the cachectic group. |
| PubMedID- 21218002 | [50–52] barber et al.,[53] demonstrated that an epa-enriched supplement added to the diet may reverse cachexia in patients with advanced pancreatic cancer. |
| PubMedID- 24404136 | In pancreatic cancer patients with cachexia, no difference in the ratio of fast/slow myosin isoform was demonstrated compared with controls [6]. |
| PubMedID- 22511317 | Neural invasion induces cachexia via astrocytic activation of neural route in pancreatic cancer. |
| PubMedID- 25893413 | Showed that pancreatic cancer patients with cachexia had a higher rate of more progressed tumor stages and a worse nutritional status.20 selection of patients with increased risk for poor postoperative outcome within this vulnerable group therefore is important. |
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