PedAM
Pediatric Disease Annotations & Medicines
| Disease | ovarian cancer |
| Phenotype | C1333990|lynch syndrome |
| Sentences | 13 |
| PubMedID- 21388660 | Conclusion: the combined data from our cohorts demonstrate that ovarian cancer associated with lynch syndrome typically presents at young age as early-stage, non-serous tumors, which implicates that a family history of colorectal and endometrial cancer should be specifically considered in such cases. |
| PubMedID- 26064726 | Currently, early cancer screening is encouraged if there has been a case of juvenile gastrointestinal cancer, endometrial cancer, or ovarian cancer with suspicion of lynch syndrome in the family history, or breast cancer with familial aggregation. |
| PubMedID- 22808608 | This is a maternal history of a 27-year-old woman sharing the destiny of her 48-year-old mother and 45-year-old aunt, both of which were suffering from lynch syndrome associated with ovarian cancer. |
| PubMedID- 24396821 | Prophylactic hysterectomy and bilateral salpingo-oophorectomy are known to prevent endometrial and ovarian cancers in patients with lynch syndrome [10]. |
| PubMedID- 25279173 | The lifetime risk for ovarian cancer in families with lynch syndrome is ~8%, which is lower than colorectal and endometrial cancers, and ovarian cancer is not listed in the amsterdam criteria ii. |
| PubMedID- 23591842 | Other hereditary epithelial ovarian cancers are attributed to lynch syndrome. |
| PubMedID- 24023337 | We report on a case of synchronous endometrial and ovarian cancer in a patient with lynch syndrome. |
| PubMedID- 23765559 | Endometrial and ovarian cancer in women with lynch syndrome: update in screening and prevention. |
| PubMedID- 23730224 | Endometrial and ovarian cancer in lynch syndrome. |
| PubMedID- 22234272 | The lifetime risk of ovarian cancer in lynch syndrome is approximately 10-12% [12], with higher risks (36%) reported in msh2 carriers [13]. |
| PubMedID- 25391615 | Given the 10 % risk of ovarian cancer associated with lynch syndrome [12], mismatch repair genes mlh1, msh2, msh6 and pms2 will be included. |
| PubMedID- 23344037 | ovarian cancer in lynch syndrome patients is characterized by distinct histology, namely, the formation of endometrioid and related clear cell types rather than serous epithelial carcinomas. |
| PubMedID- 25093288 | ovarian cancers associated with lynch syndrome are predominantly clear cell or endometrioid in histology. |
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