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PedAM

Pediatric Disease Annotations & Medicines




Disease ovarian cancer
Phenotype C0028754|obesity
Sentences 7
PubMedID- 23369448 The pro-tumorigenic role of leptin on breast, colon, prostate, and ovarian cancer in patients with obesity, mets, and t2dm was recently reviewed [85,113,114].
PubMedID- 22927847 Furthermore, a meta-analysis of ten cohort studies has shown that overweight and obesity are associated with higher ovarian cancer mortality (or, 1.6; 95% ci 1.1–2.34) and that, among patients with advanced ovarian cancer, premorbid obesity is associated with worse prognosis (or, 1.5; 95% ci 1.09–1.93) [149].
PubMedID- 24834130 The association between obesity at the time of diagnosis and ovarian cancer survival was weaker than the association between bmi evaluated before diagnosis and ovarian cancer survival.
PubMedID- 26053184 The evidence linking obesity with ovarian cancer remains controversial.
PubMedID- 24944530 It is noted that the obesity is associated with ovarian cancer, as well as breast cancer in postmenopausal women.
PubMedID- 25779915 obesity increases the risk of endometrial and ovarian cancer, and oestrogen receptor (er)-progesterone receptor (pr)-positive postmenopausal breast cancer.
PubMedID- 23652833 Although the literature to date focusing on obesity and prognosis of ovarian cancer has been inconclusive, a recent meta-analysis reported a positive relationship between early adulthood bmi and mortality among patients with ovarian cancer [10].

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