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PedAM

Pediatric Disease Annotations & Medicines




Disease ovarian cancer
Phenotype C0016412|folate deficiency
Sentences 1
PubMedID- 22605962 folate deficiency leads to ovarian cancer through two mechanisms: by inducing misincorporation of uracil into dna, thus disrupting dna integrity and dna repair; and by altering dna methylation, which can alter expression of critical tumor suppressor genes and proto-oncogenes [8–10].

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