Disease | ovarian cancer |
Phenotype | C0016412|folate deficiency |
Sentences | 1 |
PubMedID- 22605962 | folate deficiency leads to ovarian cancer through two mechanisms: by inducing misincorporation of uracil into dna, thus disrupting dna integrity and dna repair; and by altering dna methylation, which can alter expression of critical tumor suppressor genes and proto-oncogenes [8–10]. |
Page: 1