PedAM
Pediatric Disease Annotations & Medicines
| Disease | osteoporosis |
| Phenotype | C0039730|thalassemia |
| Sentences | 10 |
| PubMedID- 20976089 | It is obvious that osteoporosis in thalassemia is of multifactorial etiology and of complex mechanism which need to be clarified. |
| PubMedID- 26199898 | Local reduction of tgf-β in the bone marrow is a likely risk factor of osteoporosis in patients with thalassemia (26). |
| PubMedID- 22778734 | He prevalence of osteoporosis is high in patients with thalassemia major, possibly related to delayed puberty. |
| PubMedID- 25849944 | The reported frequency of osteoporosis, in thalassemia mayor patients, despite adequate transfusion and iron chelation therapy, varies from 13.6% to 50% with an additional 45% affected by osteopenia [67]. |
| PubMedID- 25002928 | Haticehamarat, et al studied frequency of osteoporosis in thalassemia major patients in turkey and showed that among25 patients with thalassemia major (14 men, 11 women) 16 patients had osteoporosis, where as 9 patients had osteopenia (18). |
| PubMedID- 24575552 | osteoporosis in thalassemia major: an update and the i-cet 2013 recommendations for surveillance and treatment. |
| PubMedID- 23652868 | In a previous study aimed at comparing dxa and quantitative computed tomography (qct), mylona and colleagues observed a strong difference in the prevalence of osteopenia and osteoporosis in patients with β-thalassemia according to the technique used. |
| PubMedID- 25216685 | Iron overload causes osteoporosis in thalassemia major patients through interaction with transient receptor potential vanilloid type 1 (trpv1) channels. |
| PubMedID- 22581647 | We conclude that circulating sclerostin is elevated in thalassemia patients with osteoporosis and correlated with their bmd, but it was not reduced post zoledronic acid administration. |
| PubMedID- 20694183 | In a study by otrock et al,60 18 thalassemia patients with osteoporosis were given zol 4 mg iv every 3 months over a period of 12 months. |
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