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PedAM

Pediatric Disease Annotations & Medicines




Disease osteoporosis
Phenotype C0028754|adiposity
Sentences 2
PubMedID- 22724005 It has been shown that reduction in trabecular bone in osteoporosis is associated with increased adiposity in bone marrow, which could be due to transcriptional switch in favor of adipogenesis instead of osteoblastogenesis of bone marrow precursor cells [6], [7].
PubMedID- 21717722 Among premenopausal women, central obesity and total adiposity were associated with osteoporosis in the hip (or 1.9; ci95% 1.1-3.9 and or 2.1; ci95% 1.2-8.7) and femoral areas (or 2.1; ci95% 1.2-4.1 and or 2.3; ci95% 1.3-7.1); t2d remained as protective factor (or 0.7; ci95% 0.5-0.9 and or 0.6; ci95% 0.4-0.9).

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